PPIB Antikörper (C-Term)

Produktnummer ABIN3042869

Produktdetails anti-PPIB Antikörper

Target: PPIB (Cyclophilin B (PPIB))

Bindungsspezifität: AA 176-196, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase B(PPIB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: MEVVRKVEST KTDSRDKPLK D

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase B(PPIB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: peptidylprolyl isomerase B(cyclophilin B)
Protein Name: Peptidyl-prolyl cis-trans isomerase B

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cyclophilin B(176-196aa MEVVRKVESTKTDSRDKPLKD), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for PPIB is approximately 1.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Predicted Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PPIB

Target: PPIB (Cyclophilin B (PPIB))

Andere Bezeichnung: PPIB (PPIB Produkte)

Synonyme: cypb antikoerper, scylp antikoerper, cyp-s1 antikoerper, PPIB antikoerper, Ppib antikoerper, ACYPI004891 antikoerper, AA408962 antikoerper, AA553318 antikoerper, AI844835 antikoerper, Cphn-2 antikoerper, Cphn2 antikoerper, CyP-20b antikoerper, CypB antikoerper, Scylp antikoerper, CYP-S1 antikoerper, CYPB antikoerper, OI9 antikoerper, SCYLP antikoerper, cb87 antikoerper, sb:cb87 antikoerper, wu:fa97f08 antikoerper, zgc:73214 antikoerper, zgc:86796 antikoerper, peptidylprolyl isomerase B antikoerper, peptidylprolyl isomerase B (cyclophilin B) antikoerper, peptidylprolyl isomerase B L homeolog antikoerper, ppib antikoerper, PPIB antikoerper, Ppib antikoerper, CC1G_03223 antikoerper, ppib.L antikoerper

Hintergrund: Peptidyl-prolyl cis-trans isomerase B, also known as CYPB, is an enzyme that in humans is encoded by the PPIB gene. This gene is mapped to 15q22.31. The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

Synonyms: AA408962 antibody|AA553318 antibody|AI844835 antibody|Cphn 2 antibody|Cphn2 antibody|Cyclophilin B antibody|Cyclophilin like protein antibody|CyP 20b antibody|CYP S1 antibody|CYP-S1 antibody|CYPB antibody|EC 5.2.1.8 antibody|MGC14109 antibody|MGC2224 antibody|OI9 antibody|peptidyl prolyl cis trans isomerase B antibody|Peptidyl prolyl cis trans isomerase B precursor antibody|Peptidyl-prolyl cis-trans isomerase B antibody|Peptidyl-prolyl cis-trans isomerase B precursor antibody|peptidylprolyl isomerase B(cyclophilin B) antibody|Peptidylprolyl isomerase B antibody|PPIase antibody|PPIase B antibody|PPIB antibody|PPIB_HUMAN antibody|Rotamase antibody|Rotamase B antibody|S cyclophilin antibody|S-cyclophilin antibody|SCYLP antibody

UniProt: P23284