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Lamin B1 Antikörper (AA 266-583)

LMNB1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042505
  • Target Alle Lamin B1 (LMNB1) Antikörper anzeigen
    Lamin B1 (LMNB1)
    Bindungsspezifität
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 266-583
    Reaktivität
    • 69
    • 39
    • 37
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 51
    • 21
    • 1
    Kaninchen
    Klonalität
    • 49
    • 24
    Polyklonal
    Konjugat
    • 61
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Lamin B1 Antikörper ist unkonjugiert
    Applikation
    • 57
    • 27
    • 22
    • 21
    • 16
    • 14
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Lamin-B1(LMNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Lamin-B1(LMNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: lamin B1
    Protein Name: Lamin-B1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human Lamin B1 recombinant protein (Position: Q266-C583). Human Lamin B1 shares 95.9% and 95% amino acid (aa) sequence identity with mouse and rat Lamin B1, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product LMNB1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Chen, Luo, Lin, Kuang, Song: "Simulated microgravity inhibits osteogenic differentiation of mesenchymal stem cells via depolymerizing F-actin to impede TAZ nuclear translocation." in: Scientific reports, Vol. 6, pp. 30322, (2018) (PubMed).

    Timoshevskiy, Herdy, Keinath, Smith: "Cellular and Molecular Features of Developmentally Programmed Genome Rearrangement in a Vertebrate (Sea Lamprey: Petromyzon marinus)." in: PLoS genetics, Vol. 12, Issue 6, pp. e1006103, (2017) (PubMed).

    Shen, Sun, Xia, Meng, Lei, Zhao, Tang, Xue, Chen: "Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose." in: International journal of molecular medicine, Vol. 38, Issue 3, pp. 729-36, (2017) (PubMed).

    Chen, Jiang, Gu, Lai, Liu, Zhang: "Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway." in: Environmental toxicology, Vol. 32, Issue 8, pp. 2004-2020, (2017) (PubMed).

    Zhang, Zhang, Zhang, Jiao, Zhang, Wang, Gong: "Glutamine ameliorates lipopolysaccharide-induced cardiac dysfunction by regulating the toll-like receptor 4/mitogen-activated protein kinase/nuclear factor-kB signaling pathway." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5825-5832, (2017) (PubMed).

    Tang, Wang, Chen, Xu, Ye: "Clinicopathologic and prognostic significance of p21 (Cip1/Waf1) expression in bladder cancer." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4999-5007, (2016) (PubMed).

    Chen, Lai, Yang, Ruan, Chaugai, Ning, Chen, Wang: "Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1." in: British journal of pharmacology, Vol. 173, Issue 3, pp. 545-61, (2016) (PubMed).

    Bai, Zhang, Shen, Sun, Xia, Zhang, Liu, Wang, Yuan: "Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart." in: Scientific reports, Vol. 6, pp. 22068, (2016) (PubMed).

    Wu, Liu, Duan, Gao, Li, Wang, Song, Shao, Yang, Yang: "The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration." in: Scientific reports, Vol. 6, pp. 30563, (2016) (PubMed).

    Shen, Wang, Wang, Wang, Yang, Shen, Wang, Guo, Liu, Xia, Jia, Wang: "Activation of volume-sensitive outwardly rectifying chloride channel by ROS contributes to ER stress and cardiac contractile dysfunction: involvement of CHOP through Wnt." in: Cell death & disease, Vol. 5, pp. e1528, (2015) (PubMed).

    Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." in: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, (2014) (PubMed).

    Liu, Ma, Wu, Li, Zhang, Han, Wang, Reindl, Wu, Ma: "Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-?B signaling." in: BMC cancer, Vol. 14, pp. 686, (2014) (PubMed).

    Gao, Wu, Liu, Li, Song, Teng, Sheng, Liu, Yao, Chen, Jiang, Chen, Huang: "Interaction of NS2 with AIMP2 facilitates the switch from ubiquitination to SUMOylation of M1 in influenza A virus-infected cells." in: Journal of virology, Vol. 89, Issue 1, pp. 300-11, (2014) (PubMed).

    Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).

    Zhang, Zhou, Wu, Zhang, Chen, Zha, Niu, Lu, Hao, Sun, Sun, Peng, Wang: "Cellular pharmacokinetic mechanisms of adriamycin resistance and its modulation by 20(S)-ginsenoside Rh2 in MCF-7/Adr cells." in: British journal of pharmacology, Vol. 165, Issue 1, pp. 120-34, (2012) (PubMed).

  • Target
    Lamin B1 (LMNB1)
    Andere Bezeichnung
    LMNB1 (LMNB1 Produkte)
    Synonyme
    MGC52550 antikoerper, Lamin-L(I) antikoerper, lamin-b antikoerper, lmn antikoerper, lmn2 antikoerper, lmnb antikoerper, LMNB1 antikoerper, ADLD antikoerper, LMN antikoerper, LMN2 antikoerper, LMNB antikoerper, fc06g01 antikoerper, wu:fc06g01 antikoerper, lamin B1 L homeolog antikoerper, lamin B1 antikoerper, lmnb1.L antikoerper, lmnb1 antikoerper, LMNB1 antikoerper, Lmnb1 antikoerper
    Hintergrund
    Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

    Synonyms: ADLD antibody|lamin B1 antibody|Lamin-B1 antibody|LMN antibody|LMN2 antibody|LMNB antibody| Lmnb1 antibody|LMNB1_HUMAN antibody| MGC111419 antibody|OTTHUMP00000159218 antibody
    Gen-ID
    4001
    UniProt
    P20700
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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