HSD17B10 Antikörper (AA 48-261)

Produktnummer ABIN3042460

Produktdetails anti-HSD17B10 Antikörper

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Bindungsspezifität: AA 48-261

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for 3-hydroxyacyl-CoA dehydrogenase type-2(HSD17B10) detection. Tested with WB, IHC-P in Human,Mouse.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for 3-hydroxyacyl-CoA dehydrogenase type-2(HSD17B10) detection. Tested with WB, IHC-P in Human,Mouse.
Gene Name: hydroxysteroid (17-beta) dehydrogenase 10
Protein Name: 3-hydroxyacyl-CoA dehydrogenase type-2

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ERAB recombinant protein (Position: E48-P261). Human ERAB shares 87% and 88% amino acid (aa) sequence identity with mouse and rat ERAB, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for ERAB is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Andere Bezeichnung: HSD17B10 (HSD17B10 Produkte)

Synonyme: hadh2 antikoerper, im:6899159 antikoerper, wu:fj61f03 antikoerper, zgc:101605 antikoerper, abad antikoerper, camr antikoerper, erab antikoerper, hcd2 antikoerper, hsd10 antikoerper, mhbd antikoerper, mrpp2 antikoerper, mrx17 antikoerper, mrx31 antikoerper, mrxs10 antikoerper, schad antikoerper, sdr5c1 antikoerper, HADH2 antikoerper, HSD17B10 antikoerper, 17b-HSD10 antikoerper, ABAD antikoerper, CAMR antikoerper, DUPXp11.22 antikoerper, ERAB antikoerper, HCD2 antikoerper, MHBD antikoerper, MRPP2 antikoerper, MRX17 antikoerper, MRX31 antikoerper, MRXS10 antikoerper, SCHAD antikoerper, SDR5C1 antikoerper, 17bHSD10 antikoerper, Ads9 antikoerper, Hadh2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 antikoerper, hydroxysteroid 17-beta dehydrogenase 10 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antikoerper, HSD17B10 antikoerper, hsd17b10 antikoerper, hsd17b10.L antikoerper, Hsd17b10 antikoerper

Hintergrund: ERAB is also known as HSD17B10 or HADH2. This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Synonyms: 17 beta hydroxysteroid dehydrogenase 10 antibody|17 beta hydroxysteroid dehydrogenase type 10 antibody|17-beta-HSD 10 antibody|17-beta-hydroxysteroid dehydrogenase 10 antibody|17b HSD10 antibody|3 hydroxy 2 methylbutyryl CoA dehydrogenase antibody|3 hydroxyacyl CoA dehydrogenase type 2 antibody|3 hydroxyacyl CoA dehydrogenase type II antibody|3-hydroxy-2-methylbutyryl-CoA dehydrogenase antibody|3-hydroxyacyl-CoA dehydrogenase type II antibody|3-hydroxyacyl-CoA dehydrogenase type-2 antibody|AB binding alcohol dehydrogenase antibody|ABAD antibody|Ads9 antibody|Amyloid beta binding polypeptide antibody|Amyloid beta peptide binding alcohol dehydrogenase antibody|Amyloid beta peptide binding protein antibody|CAMR antibody|DUPXp11.22 antibody|Endoplasmic Reticulum Amyloid Binding Protein antibody|Endoplasmic reticulum associated amyloid beta peptide binding protein antibody|Endoplasmic reticulum-associated amyloid beta-peptide-binding protein antibody|ER associated amyloid beta-binding protein antibody|ERAB antibody|HADH 2 antibody|HADH2 antibody|HCD 2 antibody|HCD2 antibody|HCD2_HUMAN antibody|Hsd17b10 antibody|Hydroxyacyl CoA Dehydrogenase type II antibody|Hydroxyacyl Coenzyme A dehydrogenase type II antibody|Hydroxysteroid (17 beta) dehydrogenase 10 antibody|Mental retardation X linked syndromic 11 antibody|MHBD antibody|Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase antibody|Mitochondrial ribonuclease P protein 2 antibody|Mitochondrial RNase P protein 2 antibody|MRPP2 antibody|MRX17 antibody|SCHAD antibody|SDR5C1 antibody|Short chain dehydrogenase/reductase family 5C member 1 antibody|Short chain L 3 hydroxyacyl CoA dehydrogenase type 2 antibody|Short chain type dehydrogenase/reductase XH98G2 antibody|Short-chain type dehydrogenase/reductase XH98G2 antibody|Type 10 17b HSD antibody|Type 10 17beta hydroxysteroid dehydrogenase antibody|Type II HADH antibody|XH98G2 antibody

Gen-ID: 3028

UniProt: Q99714