LIM Domain Binding 2 (LDB2) Antikörper

Antigen: LIM Domain Binding 2 (LDB2)

Synonyme: LDB1, CLIM1, Ldb3, CLP-36, AI035351, AW146358, LDB2, CLIM-1, MGC127025

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunfluoreszenz (IF), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN302913

Produktbeschreibung

Produktmerkmale: Synonyms: LDB2, CLIM1, LIM domain-binding protein 2, Carboxyl-terminal LIM domain-binding protein1, CLIM-1, LIM domain-binding factor CLIM1

Weitere Bezeichnung: LDB2

Swiss-Prot: O43679

Immunogen: Synthetic peptide

Kreuzreaktivität: Human, Maus

Beschreibung: LDB2 (LIM homeobox protein cofactor CLIM-1a). It is suggested that LIM domain bindingproteins (LDB1, LDB2 and LDB3) act synergistically to enhance transcriptional efficiency byacting as co-factors for LIM homeodomain and Otx class transcription factors both of whichhave essential roles in development. LDB2 is a close homologue of LDB1. LDBs arehomologs of the Drosophila Chip protein. Three members of the ldb gene family (Ldb1,Ldb2 and Ldb3) from the zebrafish, Danio rerio, share 95%, 73% and 62% amino acididentity with mouse Ldb1, respectively.

Spezifität: This antibody reacts to aa 107-120 of LDB2. Species: Human, Mouse. Others not tested.

Anwendungen

Applikationshinweise: Immunofluorescence. Immunohistochemistry on paraffin sections: 5 ug/ml. Western Blot: 1: 500 - 1: 2000. ELISA: 1: 5000 - 1: 20000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Reinigung: Aff - Purified

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01%(w/v) Sodium Azide

Lagerung: Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Forschungsgebiet: Chromatin und nukleäre Signaltransduktion, Transkriptionsfaktoren

Beschränkungen: Nur für Forschungszwecke einsetzbar