CLEC1A Antikörper (N-Term)

Produktnummer ABIN3024556

Produktdetails anti-CLEC1A Antikörper

Target: CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLEC1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A purified antibody

Immunogen: A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CLEC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CLEC1A

Target: CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))

Andere Bezeichnung: CLEC1 (CLEC1A Produkte)

Synonyme: RGD1566110 antikoerper, CLEC1 antikoerper, 5930406N14Rik antikoerper, C-type lectin domain family 1, member A antikoerper, C-type lectin domain family 1 member A antikoerper, C-type lectin domain family 1, member a antikoerper, Clec1a antikoerper, CLEC1A antikoerper

Hintergrund: CLEC1 is a C-type lectin receptor and part of the 'Dectin-1 cluster' subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.

Gen-ID: 51267