Uroplakin 3A Antikörper (AA 260-279)

Produktnummer ABIN3024030

Produktdetails anti-Uroplakin 3A Antikörper

Target: Uroplakin 3A (UPK3A)

Bindungsspezifität: AA 260-279

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Uroplakin 3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: Protein A affinity chromatography

Immunogen: A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,WB: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Uroplakin 3A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Andere Bezeichnung: Uroplakin 3A (UPK3A Produkte)

Hintergrund: Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.

Gen-ID: 7380