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IL-25 Antikörper (AA 115-132)

IL25 Reaktivität: Human, Maus WB, IHC (p) Wirt: Maus Monoclonal 68C1039-2 unconjugated
Produktnummer ABIN302245
  • Target Alle IL-25 (IL25) Antikörper anzeigen
    IL-25 (IL25) (Interleukin 25 (IL25))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 115-132
    Reaktivität
    • 57
    • 28
    • 20
    • 1
    Human, Maus
    Wirt
    • 44
    • 18
    • 6
    • 1
    Maus
    Klonalität
    • 47
    • 22
    Monoklonal
    Konjugat
    • 34
    • 6
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-25 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 30
    • 22
    • 12
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects Interleukin 17E (IL17E) (IL25).
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    Produktmerkmale
    Synonyms: IL-25, IL17E, IL-17E, Interleukin-17E
    Aufreinigung
    Protein G Chromatography.
    Immunogen
    A synthetic peptide of amino acids 115-132, obtained from the human IL-17E proteinsequence.
    Klon
    68C1039-2
    Isotyp
    IgG1
    Top Product
    Discover our top product IL25 Primärantikörper
  • Applikationshinweise
    Western blot (2 μg/mL). Immunohistochemistry on Paraffin Sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or(in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    IL-25 (IL25) (Interleukin 25 (IL25))
    Andere Bezeichnung
    Interleukin-25 / IL25 (IL25 Produkte)
    Synonyme
    IL17E antikoerper, IL-17e antikoerper, Il17e antikoerper, IL25 antikoerper, RGD1561632 antikoerper, interleukin 25 antikoerper, IL25 antikoerper, Il25 antikoerper
    Hintergrund
    Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated by Shi, et al and Lee, et al. and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Exposure of mice to IL17 resulted in a Th-2 like response characterized by increased serum IgE, IgG1 and IgA levels, blood eosinophilia, increased lymphocytes and neutrophils, and pathological changes in the tissues that included eosinophilic infiltrates, increased mucus production, B-lymphocyte hyperplasia and epithelial cell hyperplasia/hypertrophy.Synonyms: IL-17E, IL-25, IL17E, Interleukin-17E
    Gen-ID
    64806
    UniProt
    Q9H293
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