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Endoglin Antikörper (PE)

ENG Reaktivität: Human, Schwein FACS Wirt: Maus Monoclonal MEM-229 PE
Produktnummer ABIN302200
  • Target Alle Endoglin (ENG) Antikörper anzeigen
    Endoglin (ENG)
    Reaktivität
    • 178
    • 67
    • 44
    • 17
    • 10
    • 3
    • 2
    • 1
    Human, Schwein
    Wirt
    • 107
    • 93
    • 21
    • 1
    • 1
    Maus
    Klonalität
    • 115
    • 107
    • 1
    Monoklonal
    Konjugat
    • 93
    • 28
    • 26
    • 26
    • 15
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Endoglin Antikörper ist konjugiert mit PE
    Applikation
    • 153
    • 134
    • 62
    • 58
    • 37
    • 21
    • 19
    • 15
    • 15
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognizes CD105 (Endoglin), a 180 kDa type I integral membrane homodimer glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow, it is also present on syncytiotrophoblast on placenta throughout pregnancy.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human and Porcine.
    Produktmerkmale
    Synonyms: ENG, END, HHT1, ORW, ORW1
    Aufreinigung
    Size-Exclusion Chromatography
    Immunogen
    Recombinant Vaccinia virus containing the Human CD105 (L-isoform) cDNA
    Klon
    MEM-229
    Isotyp
    IgG2a
    Top Product
    Discover our top product ENG Primärantikörper
  • Applikationshinweise
    Flow Cytometry analysis of Human blood cells using 20 μL reagent/100 μL of whole blood or10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    Endoglin (ENG)
    Andere Bezeichnung
    CD105 / Endoglin (ENG Produkte)
    Synonyme
    ENG antikoerper, MGC137842 antikoerper, DKFZp469D0419 antikoerper, END antikoerper, HHT1 antikoerper, ORW1 antikoerper, AI528660 antikoerper, AI662476 antikoerper, CD105 antikoerper, S-endoglin antikoerper, endoglin antikoerper, ENG antikoerper, Eng antikoerper
    Hintergrund
    CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbR-2 as a receptor for TGFb-1 and TGFb-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFb-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.Synonyms: END, ENG, HHT1, ORW, ORW1
    UniProt
    P17813
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