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Hexokinase 2 Antikörper (AA 1-120)

HK2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3021256
  • Target Alle Hexokinase 2 (HK2) Antikörper anzeigen
    Hexokinase 2 (HK2)
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-120
    Reaktivität
    • 79
    • 30
    • 24
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 68
    • 20
    Kaninchen
    Klonalität
    • 68
    • 20
    Polyklonal
    Konjugat
    • 53
    • 8
    • 8
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Hexokinase 2 Antikörper ist unkonjugiert
    Applikation
    • 71
    • 38
    • 36
    • 13
    • 12
    • 11
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    MIASHLLAYF FTELNHDQVQ KVDQYLYHMR LSDETLLEIS KRFRKEMEKG LGATTHPTAA VKMLPTFVRS TPDGTEHGEF LALDLGGTNF RVLWVKVTDN GLQKVEMENQ IYAIPEDIMR
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Hexokinase II (NP_000180.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Guo, Yao, Zhan, Hu, Yue, Cheng, Liu, Ye, Qing, Zhang, Liu: "N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation." in: Toxicology and applied pharmacology, Vol. 280, Issue 3, pp. 475-83, (2014) (PubMed).

  • Target
    Hexokinase 2 (HK2)
    Andere Bezeichnung
    HK2 (HK2 Produkte)
    Synonyme
    HKII antikoerper, HXK2 antikoerper, AI642394 antikoerper, hexokinase-2 antikoerper, fi09d05 antikoerper, fi17h06 antikoerper, wu:fi09d05 antikoerper, wu:fi17h06 antikoerper, wu:fi31b04 antikoerper, zgc:55926 antikoerper, HK2 antikoerper, ARABIDOPSIS THALIANA HEXOKINASE 2 antikoerper, ATHXK2 antikoerper, F6F22.11 antikoerper, F6F22_11 antikoerper, HEXOKINASE 2 antikoerper, hexokinase 2 antikoerper, StHK2 antikoerper, hexokinase 2 antikoerper, hexokinase-2 antikoerper, hexokinase 2 L homeolog antikoerper, HK2 antikoerper, Hk2 antikoerper, hk2 antikoerper, HXK2 antikoerper, LOC100032849 antikoerper, hk2.L antikoerper, hxk2 antikoerper, LOC102577690 antikoerper
    Hintergrund
    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.,HK2,HKII,HXK2,hexokinase-2,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,Cardiovascular,Heart,Cardiac metabolism,HK2
    Molekulargewicht
    102 kDa
    Gen-ID
    3099
    UniProt
    P52789
    Pathways
    PI3K-Akt Signalweg, Carbohydrate Homeostasis, Warburg Effekt
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