Osteoprotegerin Antikörper (AA 20-37)

Produktnummer ABIN296455

Dieser Maus Monoklonal Antikörper detektiert spezifisch Osteoprotegerin in WB, IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Osteoprotegerin Antikörper (AA 20-37) (ABIN296455)

Target: Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Osteoprotegerin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 98A1071

Produktdetails anti-Osteoprotegerin Antikörper

Bindungsspezifität: AA 20-37

Spezifität: The Osteoprotegerin antibody, clone 98A1071, detects all forms of Osteoprotegerin including monomeric, dimeric and Osteoprotegerin bound to RANKL (Vandooren, 2008) as well as Osteoprotegerin bound to TRAIL (Sandra, 2006).

Homologie: Percent identity by BLAST analysis: Human, Gibbon (100%) Monkey (94%) Marmoset, Panda, Dog, Horse, Pig, Opossum (89%) Mouse, Rat, Elephant, Bovine (83%).

Aufreinigung: Protein G purified

Immunogen: A peptide corresponding to the amino acids 20-37 TQETFPPKYLHYDEETSH of human OPG. The specificity was tested on recombinant OPG by western blot analysis. Percent identity by BLAST analysis: Human, Gibbon (100%), Monkey (94%), Marmoset, Panda, Dog, Horse, Pig, Opossum (89%), Mouse, Rat, Elephant, Bovine (83%).

Type of Immunogen: Recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.05 % BSA, 0.05 % sodium azide. Sourced in TCS.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Osteoprotegerin

Target: Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))

Andere Bezeichnung: Osteoprotegerin / OPG

Substanzklasse: Chemical

Hintergrund: Name/Gene ID: TNFRSF11B
Family: TNF Receptor

Synonyms: TNFRSF11B, OCIF, OPG, Osteoprotegerin, TR1

Gen-ID: 4982

UniProt: O00300