SCN5A Antikörper (AA 1548-1558)

Produktnummer ABIN290512

Dieser Ziege Polyklonal Antikörper detektiert spezifisch SCN5A in ELISA, IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SCN5A Antikörper (AA 1548-1558) (ABIN290512)

Target: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SCN5A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SCN5A Antikörper

Bindungsspezifität: AA 1548-1558

Spezifität: Human SCN5A / Nav1.5. This antibody is expected to recognise all reported isoforms (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine, Dog, Horse, Pig, Opossum (91%) Turkey, Chicken, Pufferfish, Slime mold (82%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-ETDDQSPEKIN from an internal region of human SCN5A / Nav1.5 (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1, NP_001153632.1, NP_001153633.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine, Dog, Horse, Pig, Opossum (91%), Turkey, Chicken, Pufferfish, Slime mold (82%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 - 10 μg/mL), Peptide-ELISA (1:32000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5-10 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu SCN5A

Target: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Andere Bezeichnung: SCN5A / Nav1.5

Hintergrund: Name/Gene ID: SCN5A
Subfamily: Sodium channel - voltage-gated
Family: Ion Channel

Synonyms: SCN5A, CDCD2, CMPD2, HB1, HB2, HH1, HBBD, Nav1.5, IVF, RSKM2X, SCAL, Scn2x, LQT3, SSS1, MH1, VF1, PFHB1, RATRSKM2X, SkM2, CMD1E, ICCD, RH1, RSkM2

Gen-ID: 6331

NCBI Accession: NP_932173, NP_000326, NP_001092874, NP_001092875, NP_001153632, NP_001153633

UniProt: Q14524