KOR Antikörper

Antigen: KOR

Klonalität: Monoklonal (5E3)

Wirt: Maus

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS), Western Blot (WB), Immunpräzipitation (IP)

Produktnummer: ABIN290066

Produktbeschreibung

Immunogen: hKOR expressing cell line

Format: Affinity-purified

Isotyp: IgG1 kappa  (Passende Sekundärantikörper)

Klon: 5E3

Beschreibung: OPRK1 (opioid receptor, kappa 1), also known as KOR, belongs to the rhodopsin subfamily of G-protein-coupled receptor (GPCR) family. OPRK1 is consist of 380amino acids and is widely expressed in the nervous system. OPRK1 is activated by endogenous opioid peptide agonists derived from prodynorphin. Stimulation ofOPRK1 in vivo produces many effects, including analgesia, water diuresis, dysphoria, antipruritic effects, and attenuation of cocaine craving in addicts. In addition,some studies reported that OPRK1 is associated with alcohol intake and the risk for alcohol dependence and activation of OPRK1 in human microglia suppressesHIV-1 expression.

Anwendungen

Applikationshinweise: WB 5.0 ug/ml. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 1.0 ug/ml. Neutralization Not tested. IP 5.0 ug/ml.

Konzentration: 0.25 mg/ml

Reinigung: Protein G

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Immunocytochemical staining of HEK293T cells overexpressing human KOR