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Antikörper
»
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) Antikörper
omega-3 Fatty Acid Receptor 1 (O3FAR1) Antikörper
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| Klonalität |
Monoklonal (2B6) |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN290065 |
| Menge |
25 ug (0.25 mg/ml) |
| Preis |
793,85 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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GPR120
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Immunogen
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Partial peptide of Human GPR120
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Format
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Affinity-purified
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Isotyp
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IgG2a kappa (Passende Sekundärantikörper)
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Klon
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2B6
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Beschreibung
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GPR120 is a member of G protein-coupled receptor (GPCR) family and functions as a specific receptor for unsaturated long-chain free fatty acids (FFAs) such aspalmitoleic acid, alpha-linolenic acid, docosahexaenoic acid. The expression of GPR120 is widely detected in various tissues, and GPR120 is highly expressed in th epituitary, lung, small intestine, colon, and adipose tissues.It has been shown that the stimulation of GPR120 by FFAs promotes the secretion of GLP-1, known as the most potent insulinotropic incretin, from the gastrointestinal tract. It has been also demonstrated that FFAs stimulate the ERK and PI3K-Akt pathways through GPR120 and lead to anti-apoptotic effect in enteroendocrine cell line, and that GPR120 regulates adipogenic process such as adipocyte development and differentiation. In addition, a study suggested that GPR120 is expressed in the taste bud cells in circumvallate papillae to sense dietary fat.This antibody is specific to GPR120 and will be useful for research on diabetes, obesity.
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Applikationshinweise
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WB Not tested. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 1.0-5.0 ug/ml. Neutralization Not tested. IP Not tested
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Konzentration
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0.25 mg/ml
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Reinigung
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Protein G
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Buffer
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PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
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Lagerung
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Store below -20
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "omega-3 Fatty Acid Receptor 1 (O3FAR1)", Typ "Antikörper" finden
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Wirte
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Kaninchen (13), Ziege (2), Maus (1)
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Reaktivitäten
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Human (15), Maus (6), Ratte (Rattus) (6)
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Applikationen
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Immunhistochemie (Paraffinschnitte) (IHC (p)) (6), Western Blot (WB) (6), Immunfluoreszenz (IF) (5), Enzyme Immunoassay (EIA) (3), Dot Blot (Dot) (1), ELISA (1), Durchflusszytometrie (FACS) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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Epitope
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C-Term (1)
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Alternativen 
