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Antikörper
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anti-Intercellular Adhesion Molecule 1 (ICAM1) Antikörper
Intercellular Adhesion Molecule 1 (ICAM1) Antikörper
| Antigen |
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| Synonyme |
BB2, CD54, P3.58, Ly-47, Icam-1, MALA-2, MGC6195, ICAM-1, ICAM1, ICAM |
| Klonalität |
Monoklonal (YUK11) |
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Wirt
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Reaktivität
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Human (418), Maus (193), Ratte (Rattus) (116), Rind (Kuh) (60), Schwein (45), Kaninchen (43), Hund (39), Schaf (19), Pferd (16), Huhn (4), Meerschweinchen (2), Hamster (2), Affe (2), Fisch (1)
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Applikation
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 Alternativen Durchflusszytometrie (FACS), Immunpräzipitation (IP)
Durchflusszytometrie (FACS) (465), Immunfluoreszenz (IF) (160), Western Blot (WB) (155), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (129), Immunpräzipitation (IP) (114), Immunhistochemie (Paraffinschnitte) (IHC (p)) (85), ELISA (63), Funktionale Studien (Func) (33), Immunhistochemie (IHC) (28), Enzyme Immunoassay (EIA) (24), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (13), Immunzytochemie (ICC) (11), Blocking Antibody (Inhibition) (10), Blockierende Antikörper (Inhibition) (10), Immunoelectron Microscopy (IEM) (7), Immunohistochemistry (Fixed) (IHC (fx)) (5), Intrazelluläre Durchflusszytometrie (ICFC) (4), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2)
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| Produktnummer |
ABIN290055 |
| Menge |
50 ug (0.25 mg/ml) |
| Preis |
793,85 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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CD54(ICAM-1)
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Immunogen
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human cancer cel line
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Format
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Affinity-purified
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Isotyp
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IgG2a kappa (Passende Sekundärantikörper)
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Klon
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YUK11
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Beschreibung
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CD54 (also known as ICAM-1: intercellular adhesion molecule-1) is a transmembrane glycoprotein of the immunoglobulin superfamily ofadhesion molecules. CD54 expression is constitutive on many cell types. CD54 is a inducible ligand for LFA-1 (lymphocyte function associatedantigen) and functions cell-to-cell interactions in inflammatory and immune responses.Some studies have showed that the elevated expression of CD54 occurred in a variety of diseases, including autoimmune diseases, endocrinediseases, and some cancers as gastric, pancreatic, breast cancer. Surface expressed CD54 is apparently shed from the cells and then circulatesas soluble ICAM-1 (sICAM-1). sICAM-1 can compete with cell surface CD54 to bind LFA-1 on T lymphocytes. Shedding of CD54 by circulatingtumor cells may allow their escape from surveillance by cytotoxic T and natural killer cells, and promote metastasis. It has been suggested thatsICAM-1 levels were found to be related tumor presence, clinical stages, and grade.This antibody is specific to human CD54 and will be useful for FCM, immunoprecipitation.
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Applikationshinweise
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WB Not tested. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 1.0-5.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml
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Konzentration
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0.25 mg/ml
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Reinigung
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Protein G
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Buffer
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PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
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Lagerung
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Store below -20
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Intercellular Adhesion Molecule 1 (ICAM1)", Typ "Antikörper" finden
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Wirte
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Maus (283), Kaninchen (194), Ratte (99), Hamster (8), Schaf (1)
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Reaktivitäten
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Human (418), Maus (193), Ratte (Rattus) (116), Rind (Kuh) (60), Schwein (45), Kaninchen (43), Hund (39), Schaf (19), Pferd (16), Huhn (4), Meerschweinchen (2), Hamster (2), Affe (2), Fisch (1)
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Applikationen
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Durchflusszytometrie (FACS) (465), Immunfluoreszenz (IF) (160), Western Blot (WB) (155), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (129), Immunpräzipitation (IP) (114), Immunhistochemie (Paraffinschnitte) (IHC (p)) (85), ELISA (63), Funktionale Studien (Func) (33), Immunhistochemie (IHC) (28), Enzyme Immunoassay (EIA) (24), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (13), Immunzytochemie (ICC) (11), Blocking Antibody (Inhibition) (10), Blockierende Antikörper (Inhibition) (10), Immunoelectron Microscopy (IEM) (7), Immunohistochemistry (Fixed) (IHC (fx)) (5), Intrazelluläre Durchflusszytometrie (ICFC) (4), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2)
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Konjugate
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Biotin (60), FITC (54), PE (50), Alexa Fluor 488 (14), Alexa Fluor 647 (11), PE,Cy5 (9), APC (8), Alexa Fluor 350 (7), Alexa Fluor 555 (7), Cy3 (7), Cy5 (7), Cy5.5 (7), Cy7 (7), Gold (7), HRP (7), PE,Cy3 (7), PE,Cy5.5 (7), PE,Cy7 (7), RBITC (7), RPE (7), Alexa Flour 488 (6), Pacific Blue (3), Alexa Fluor 700 (2), Alexa Fluor 546 (1), PerCP (1)
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Epitope
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pTyr512 (9), C-Term (3), AA 253-267 (1), Domain D1 (1)
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