CD9(MRP-1) Antikörper

Antigen: CD9(MRP-1)

Klonalität: Monoklonal (6D11)

Wirt: Maus

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS), Immunpräzipitation (IP), Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN290054

Produktbeschreibung

Immunogen: human cancer cel line

Format: Affinity-purified

Isotyp: IgG2a kappa  (Passende Sekundärantikörper)

Klon: 6D11

Beschreibung: CD9 (also known as MRP-1: Motility-Related Protein 1) is a member of tetraspanin family. Tetraspanins comprise a family of over 30 membrane glycoproteins with four hydrophobic transmembrane domains. It has been reported that tetraspanins can regulate several biological andpathological process, including migration and metastasis, adhesion, cell proliferation, differentiation. The expression of many member of the familyis changed in different types of carcinomas.Clinical and pathologic findings indicate that down-regulation of CD9 correlates with tumor progression and metastasis, including melanoma, breast,lung, colon, prostate, pancreas and ovarian cancer. Moreover, transfection of CD9 inhibits cell motility and tumor metastasis.This antibody is specific to human CD9 and will be useful for FCM, immunoprecipitation, immunohistochemistry, western blotting.

Anwendungen

Applikationshinweise: WB 1.0-5.0 ug/ml. IHC 10.0 ug/ml. ICC Not tested. ELISA Not tested. FCM 1.0-5.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml

Konzentration: 0.25 mg/ml

Reinigung: Protein G

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar