Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) Antikörper

Antigen: Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1)

Synonyme: VR1, DKFZp434K0220, Vr1, Vr1l1, VR.5'sv, VR-1, OTRPC1, TRPV1beta, TRPV1alpha, TRPV1, Trpv1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN290043

Produktbeschreibung

Weitere Bezeichnung: phospho TRPV1 (VR-1)

Immunogen: Partial peptide of Rat Phospholipid scramblase 2

Format: Affinity-purified

Beschreibung: Recent work has begun to clarify the function of ionotropic receptors, which are expressed in sensory neurons and promote nociception. The most representative receptors of this class belong to TRP ion channel superfamilycomprised by seven sub-families, TRPC, TRPV, TRPP, TRPM, TRPN, TRPML and TRPA.TRPVl channels have six transmembrane domains that most probably assemble into tetramers to formnon-selective cationic channels. The first cloned TRPV receptor was TRPV1. This receptor is activated by capsaicin, protons or heat (with a threshold > ~43

Anwendungen

Applikationshinweise: Working dilution For Western blotting 0.5ug/ml

Konzentration: 0.25 mg/ml

Reinigung: This antibody was established from the serum of a rabbit immunized with the partial peptide representing phosphorylated TRPV1 at S800, and purified by peptide affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blotting Sample: phosphorylated TRPV1 at S800 in HEK293 cells. Preparation of antibodies and instruction: Dr. Makoto Tominaga at Section of Cell Signaling,Okazaki Institute for Integrative Bioscience,National Institutes of Natural Sciences