Organic Cation Transporter 3 (OCT3) Antikörper

Antigen: Organic Cation Transporter 3 (OCT3)

Synonyme: EMT, EMTH, OCT3, Oct3, Orct3, Slca22a3

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN290005

Produktbeschreibung

Weitere Bezeichnung: Organic Cation Transporter 3

Immunogen: Partial peptide of Rat Organic Cation Transporter 3

Format: Affinity-purified

Beschreibung: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for theelimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fallinto various transport systems by the transportative substrate. In particular, oraganic ion transporter familyis comprised of organic anion transport family (OAT), oraganic cation transport family (OCT),OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates ofwhich include a lot of both endogeneous and exogeneous anions.Organic Cation Transporter 3 (OCT3) is expressed in kidney, placenta and brain. In brain, OCT3 issuggested that it is involved in monoamine regulation mechanism and plays a significant role in the disposition of cationic neurotoxins.This antibody was established from the purified serum immunized with partial peptide of rat OCT3. This antibody is useful for Immnohistochemistry.

Anwendungen

Applikationshinweise: Working dilution For Immunohistochemistry , 1-5 ug/ml

Konzentration: 0.25 mg/ml

Reinigung: This antibody was purified from rabbit serum by affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Immunohistochemistry Sample: rat brain astrocyte. Preparation of antibodies and instruction: Drs. Takeda H. and Inazu M. at Department ofPharmacology, Tokyo Medical University