Jub, Ajuba Homolog (Xenopus Laevis) (JUB) Antikörper

Antigen: Jub, Ajuba Homolog (Xenopus Laevis) (JUB)

Synonyme: Ajuba, MGC15563, JUB, MGC93830, fj66b05, wu:fj66b05

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunzytochemie (ICC), Immunpräzipitation (IP)

Produktnummer: ABIN290002

Produktbeschreibung

Weitere Bezeichnung: Ajuba

Immunogen: GST-Human Ajuba fusion Protein

Format: Affinity-purified

Beschreibung: Aurora-A(Aurora-A/STK-15/Aik) encoding a centrosome-associated Ser/Thr kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. In vitro transformation activityof Aurora-A suggested to be a potential oncogene. Recent research elucidated that Ajuba, Aurora-A bindingprotein, induces the autophosphorylation and consequent activation of Aurora-A . In the future thisantibody will contribute the research progress whether Ajuba and Aurora-A are involed in tumorigenesis.This antibody is useful for immunoprecipitation and immunocytochemistry.

Anwendungen

Applikationshinweise: Working dilution For Immunoprecipitation , 10 ug/mlFor Immnocytochemistry , 2-5 ug/ml

Konzentration: 0.25 mg/ml

Reinigung: This antibody was purified from rabbit serum by affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Immnocytochemistry Sample : HeLa CellPreparation of antibodies and instruction: Dr. Saya H. and Dr. Hirota T. at Department of Tumor Genetics and Biology, Kumamoto University School of medicine.