Seven in Absentia Homolog 1 (Drosophila) (SIAH1) Antikörper

Antigen: Seven in Absentia Homolog 1 (Drosophila) (SIAH1)

Synonyme: SIAH1, siah, MGC79105, hsiah1, siah-1, humsiah, siah-1a, MGC97801

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN289989

Produktbeschreibung

Weitere Bezeichnung: Siah 1

Immunogen: Partial peptide of Human Siah 1

Format: Affinity-purified

Beschreibung: The turnover of a protein is precisely under control in the cell. Particularly, the system of controlling protein degradation via the ubiquitin-proteosome pathway is involving in many kinds of process in the cell. The Drosophila Seven in absentina (Sina) gene product originally was identified as a protein that controls cell fate decisions during eye development. Its mammalian homolog, Siah1 and Siah2, have been described that they might involve in ubiquitin-mediated proteolysis of several proteins, as well as in growth arrest andp53-induced apoptosis.This antibody is very useful for identifying the function of the mammalian Siah1 in the cell.

Anwendungen

Applikationshinweise: Working dilution Western Blotting: 0.8ug/ml

Konzentration: 0.25 mg/ml

Reinigung: This antibody was purified from rabbit serum by affinity chromatography

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western Blotting Sample: 293 cell lysate 1) control 2) Siah1 gene transgenic cell MG-132 protease inhibitor. Preparation of antibodies and instruction: Dr.Koki Moriyoshi at Department of Biological Sciences,Kyoto University Faculty of Medicine