Aurora Kinase A (AURKA) Antikörper

Antigen: Aurora Kinase A (AURKA)

Synonyme: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, IAK, Ark1, Ayk1, Stk6, AIRK1, AU019385, AW539821, Aurora-A, 87A7-9/2, AurA, ck10, ck[10], l(3)87Ac, l(3)ck10, DmelCG3068, CG3068, MGC124935, aurka, AURKA, MGC134472, aik, ark1, aura, btak, stk6, stk7, stk15, aurora2, zgc:100912

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN289985

Produktbeschreibung

Weitere Bezeichnung: Aurora-A

Immunogen: GST-Human Aurora-A fusion Protein

Format: Affinity-purified

Beschreibung: Aurora-A (Aurora-A/STK-15/Aik) encoding a centrosome-associated kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. So that, Aurora-A is a potentialoncogene. Aurora family have been identified three types (Aurora-A, B, C) which has high homologydomain in C terminal region. Aurora family is indispensable kinase that regulate the structure and functionof centrosomes and spindle. Aurora-A could be one of targeting molecule of anti-cancer therapy.This antibody was established from the purified serum of the immunized rabbit with N terminal region ofAurora-A and did not show any cross- reactivity to Aurora-B and Aurora-C. This antibody is useful forwestern blotting and immunohistochemistry.

Synonyme: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, IAK, Ark1, Ayk1, Stk6, AIRK1, AU019385, AW539821, Aurora-A, 87A7-9/2, AurA, ck10, ck[10], l(3)87Ac, l(3)ck10, DmelCG3068, CG3068, MGC124935, aurka, AURKA, MGC134472, aik, ark1, aura, btak, stk6, stk7, stk15, aurora2, zgc:100912

Anwendungen

Applikationshinweise: Working dilution For western blotting , 0.5-2 ug/mlFor Immunohistochemistry , 1-2ug/ml

Konzentration: 0.25 mg/ml

Reinigung: This antibody was purified from rabbit serum by affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Immunocytochemistry Sample : HeLa Cell. Preparation of antibodies and instruction: Dr.Saya H. and Dr.Marumoto T. at Department ofTumor Genetics and Biology, Kumamoto UniversitySchool of medicine.