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Antikörper
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anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) Antikörper
Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) Antikörper
| Antigen |
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| Synonyme |
MACS, 80K-L, PKCSL, PRKCSL, FLJ14368, FLJ90045, KINC, Macs, marcks, MGC89127, MARCKS, MGC137530 |
| Klonalität |
Monoklonal (MAR 11-2) |
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Wirt
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Reaktivität
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Human (99), Ratte (Rattus) (75), Maus (68), Rind (Kuh) (19), Hund (18), Schwein (18), Kaninchen (17), Huhn (2), Meerschweinchen (1), Säugetiere (1), Zebrafisch (Brachydanio rerio) (1)
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Applikation
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Western Blot (WB) (84), Immunfluoreszenz (IF) (59), Durchflusszytometrie (FACS) (21), ELISA (13), Immunhistochemie (Paraffinschnitte) (IHC (p)) (13), Enzyme Immunoassay (EIA) (11), Immunhistochemie (IHC) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), Immunzytochemie (ICC) (6), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN289977 |
| Menge |
50 ug (0.25 mg/ml) |
| Preis |
793,85 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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MARCKS
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Immunogen
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Partial peptide of Rat MARCKS
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Format
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Affinity-purified
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Isotyp
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IgG2a (Passende Sekundärantikörper)
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Klon
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MAR 11-2
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Beschreibung
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Myristoylated alanine-rich C kinase substrate (MARCKS), a specific substrate for protein kinase C,is abundant in the brain. MARCKS binds calmodulin under Ca2+ or actin under non-Ca2+ conditions.Phosphorylation of MARCKS (P-MARCKS) can be used as an indicator of protein kinase C activationin intact cells. It has been shown that P-MARCKS has relatively weaker binding activity to calmodulinand actin compared with MARCKS.Pathophysiologically, P-MARCS is also detected in the brain of Alzheimer
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Applikationshinweise
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Working dilution for immunohistochemistry: about 1~ 5ug/ml
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Konzentration
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0.25 mg/ml
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Reinigung
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The lymphocytes from rat, immunized with C terminal peptides of ratMARCKS, were fused to mouse myeloma SP2 cells. The cell line (MAR11/2)with positive reaction was grown in serum free medium from which theantibody was purified by Protein G affinity chromatography.
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Buffer
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PBS (containing 0.1% BSA as a stabilizer, 0.1% Proclin as a bacteriostat)
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Lagerung
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Store below -20
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS)", Typ "Antikörper" finden
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Wirte
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Kaninchen (110), Maus (7), Ratte (1)
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Reaktivitäten
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Human (99), Ratte (Rattus) (75), Maus (68), Rind (Kuh) (19), Hund (18), Schwein (18), Kaninchen (17), Huhn (2), Meerschweinchen (1), Säugetiere (1), Zebrafisch (Brachydanio rerio) (1)
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Applikationen
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Western Blot (WB) (84), Immunfluoreszenz (IF) (59), Durchflusszytometrie (FACS) (21), ELISA (13), Immunhistochemie (Paraffinschnitte) (IHC (p)) (13), Enzyme Immunoassay (EIA) (11), Immunhistochemie (IHC) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), Immunzytochemie (ICC) (6), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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pSer158 (7), pSer162 (7), pSer170 (6), Ab-162 (4), C-Term (4), N-Term (2), pS152/S156 (1), pSer152, pSer156 (1), pSer152/156 (1), pSer159/163 (1), pSer163 (1), phospho (1)
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Alternativen 
