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RAGE Antikörper

AGER Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN289974
  • Target Alle RAGE (AGER) Antikörper anzeigen
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    Reaktivität
    • 143
    • 82
    • 64
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 137
    • 11
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 131
    • 23
    • 1
    Polyklonal
    Konjugat
    • 71
    • 11
    • 10
    • 9
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RAGE Antikörper ist unkonjugiert
    Applikation
    • 127
    • 66
    • 49
    • 34
    • 27
    • 26
    • 24
    • 11
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody was purified from rabbit serum by Protein G affinity chromatography.
    Immunogen
    Partial peptide of Human RAGE
    Top Product
    Discover our top product AGER Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.25 mg/ml
    Buffer
    PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
    Konservierungsmittel
    ProClin
    Lagerung
    -20 °C
  • Target
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    Andere Bezeichnung
    RAGE (AGER Produkte)
    Synonyme
    RAGE antikoerper, AGER antikoerper, advanced glycosylation end-product specific receptor antikoerper, advanced glycosylation end product-specific receptor antikoerper, MAPK/MAK/MRK overlapping kinase antikoerper, AGER antikoerper, Ager antikoerper, LOC719012 antikoerper
    Hintergrund
    RAGE is the receptor of AGEs, advanced glycation end products with 35,000 molecularweight and was cloned from bovine lung in 1992 ( David Stern et al.,). RAGE has been foundin several tissues such as monocytes, macrophages, endothelial cells, astocytes. The ligand ofRAGE is demonstrated not only AGEs but also anfoterin, EN-RAGE,N-carboxymethyllysine(CML),beta-amyloid and so on. The accumulation of AGEs-proteins invivo has been demonstrated in several disease, it is not clear whether AGEs-proteinsaccumulated in vivo is a direct cause of the disease or rather reflects its effect. Regarding this issue, AGEs-modified proteins are known to interact with several cells by the AGEs-receptors and induce several cellular phenomena. Recently, it has been discovered that RAGE isinvolved in pathophysiological function of diabetes and Alzheimer
    Pathways
    Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine
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