CEL Antikörper (Peroxidase)

Antigen: CEL

Klonalität: Monoklonal (KNH-30)

Wirt: Maus

Reaktivität: Alle Spezies

Konjugat: Peroxidase (POD)

Applikation: Immunhistochemie (IHC), ELISA

Produktnummer: ABIN289961

Produktbeschreibung

Immunogen: CEL-BSA

Format: Affinity-purified

Isotyp: IgG1

Klon: KNH-30

Beschreibung: Reaction of protein amino groups with glucose leads, through the early products such as a Schiff base andAmadori rearrangement products, to the formation of advanced glycation end products (AGEs). Recentimmunological studies using anti-AGEs antibody (6D12) demonstrated the presence of AGEs-modified proteinsin several human tissues: human lens (nondiabetic and noncataractous), renal proximal tubules inpatients with diabetic nephropathy and chronic renal failure, diabetic retina, peripheral nerves ofdiabetic neuropathy, atherosclerotic lesions of arterial walls, beta2-microglobulin forming amyloid fibrilsin patients with hemodialysis-related amyloidosis, senile plaques of patients with Alzheimer

Anwendungen

Applikationshinweise: Working dilution for immunohistochemistry: 5-10ug/ml, for ELISA: 0.1-1.0ug/ml

Konzentration: 0.25 mg/ml

Reinigung: The splenic lymphocytes from BALB/c mouse, immunized with CEL-BSA were fused to myelomaP3U1 cells. The cell line (KNH-30) with positive reaction was grown in ascitic fluid of BALB/cmouse, from which the antibody was purified by Protein G affinity chromatography and conjugated.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar