CML Antikörper (Peroxidase)

Antigen: CML

Klonalität: Monoklonal (NF-1G)

Wirt: Maus

Reaktivität: Alle Spezies

Konjugat: Peroxidase (POD)

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN289958

Produktbeschreibung

Immunogen: CML-HSA

Format: Affinity-purified

Isotyp: IgG2a

Klon: NF-1G

Beschreibung: Reaction of protein amino groups with glucose leads, through the early products such as a Schiff base andAmadori rearrangement products, to the formation of advanced glycation end products (AGEs). Recentimmunological studies using anti-AGEs antibody (6D12) demonstrated the presence of AGEs-modified proteinsin several human tissues: human lens (nondiabetic and noncataractous), renal proximal tubules inpatients with diabetic nephropathy and chronic renal failure, diabetic retina, peripheral nerves ofdiabetic neuropathy, atherosclerotic lesions of arterial walls, beta2-microglobulin forming amyloid fibrilsin patients with hemodialysis-related amyloidosis, senile plaques of patients with Alzheimer

Anwendungen

Applikationshinweise: Working dilution for immunohistochemistry: 3-10ug/ml,

Konzentration: 0.25 mg/ml

Reinigung: The splenic lymphocytes from BALB/c mouse, immunized with CML-HSA were fused tomyeloma P3U1 cells. The cell line (NF-1G) with positive reaction was grown in ascitic fluid ofBALB/c mouse, from which the antibody was purified by Protein G affinity chromatography,and conjugated

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Lagerung: Store below -20

Beschränkungen: Nur für Forschungszwecke einsetzbar