SLC7A5 Antikörper

Produktnummer ABIN289955

Produktdetails anti-SLC7A5 Antikörper

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SLC7A5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: The spleen cells from mouse, immunized with the synthesized peptide of human C endof LAT-1, were fused with mouse P3U1 myeloma cells. The hybridoma cell line withpositive reaction was grown in ascitic fluid of BALB/c mouse, from which theantibody was purified by Peptide affinity chromatography.

Immunogen: Partial peptide of Human L-type Amino Acid Transporter 1 (LAT1)

Klon: 4D9

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Working dilution for immunohistochemistry: 2-5ug/mlFor more detail on the immunohistochemistry, refer to the immuno staining method.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/ml

Buffer: PBS (containing 0.1% BSA as a stabilizer, 0.1% Proclin as a bacteriostat)

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu SLC7A5

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Andere Bezeichnung: L-type Amino Acid Transporter 1 (LAT1) (SLC7A5 Produkte)

Synonyme: 4F2LC antikoerper, CD98 antikoerper, D16S469E antikoerper, E16 antikoerper, LAT1 antikoerper, MPE16 antikoerper, hLAT1 antikoerper, D0H16S474E antikoerper, TA1 antikoerper, JHI-21 antikoerper, SLC7A5 antikoerper, LAT-1 antikoerper, slc7a5a antikoerper, 4F2 antikoerper, 4F2HC antikoerper, AI314110 antikoerper, Cd98 antikoerper, Ly-10 antikoerper, Ly-m10 antikoerper, Ly10 antikoerper, Mdu1 antikoerper, Mgp-2hc antikoerper, NACAE antikoerper, solute carrier family 7 member 5 antikoerper, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 antikoerper, solute carrier family 7 (amino acid transporter light chain, L system), member 5 antikoerper, solute carrier family 7 member 5 S homeolog antikoerper, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antikoerper, SLC7A5 antikoerper, Slc7a5 antikoerper, slc7a5.S antikoerper, Slc3a2 antikoerper

Hintergrund: Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection ofamino acid molecule variety, and is clessfied into various transport systems by the transportative substrateselectivity and the Na+ dependence with the reflection of amino acid molecule variety.L-type amino acid transporter 1 (LAT1) is a predicted 12 membrane-spanning protein and is unique because itrequires an additional single membrane spanning protein, 4F2 heavy chain (4F2hc:CD98), for its functionalexpression. L-type is Na+ -independent neutral amino acid transporter agency and essential for the transporter oflarge neutral amino acid such as Leucine, Isoleucine, Varine through the plasma membrane. LAT1 is, thustransporter responsible for the permeation of aromatic or branched-chain amino acids and amino acid-relateddrugs such as L-DOPA. LAT has been proposed to be one of the major nutrient transport systems at theblood-brain barrier. Highly regulated nature and high level of expression in tumor cell lines, LAT is thought to beup-regulated to support the high protein synthesis for cell glowth and cell activation.This antibody has been proved to be useful for the immunohistochemistry.