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Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11) Antikörper

Antigen

Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11)

Synonyme xCT, CCBR1, sut, AI451155, 9930009M05Rik, SLC7A11, DKFZp468E122
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Applikation
Alternativen Immunhistochemie (IHC), Western Blot (WB)
Produktnummer ABIN289953
Menge 25 ug  (0.1 mg/ml)
Preis 728,99 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung Cystine / Glutamic Acid Transporter (xCT)
Immunogen Partial peptide of Mouse Cystine / Glutamic Acid Transporter (xCT)
Format Affinity-purified
Beschreibung Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection ofamino acid molecule variety, and is classfied into various transport systems by the transportative substrateselectivity and the Na+ dependence with the reflection of amino acid molecule variety.The amino acid transporter, cystine/glutamic acid transporter (xCT) for system xchas been proposed to beresponsible for the cystine transport through the plasma membrane. System xc mediates an amino acid exchange and prefers cystine and glutamate as its substrates. The transporter designated as xCT requires 4F2 heavy chain (4F2hc:CD98) for its functional expression, and belongs to the family of amino acidtransporters which associates with the type II membrane glycoproteins such as 4F2hc. In brain, it has beenproposed that system xcis up-regulated in glial cells upon the oxidative stress and plays an essential rolesto protect neurons against oxidative stress. This antibody has been proved to be useful for immunoblotting and immunohistochemistry. Considering the peptide amino acid sequence, this antibody also seems to react with human xCT.

Anwendungen

Applikationshinweise Working dilution for Immunohistochemistry: 5ug/ml ,for immunoblotting: 1ug/ml
Konzentration 0.1 mg/ml
Reinigung This antibody was purified from rabbit serum immunized with synthesized peptideof N- end of mouse xCT by peptide affinity chromatography.
Buffer PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
Lagerung Store below -20
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11)", Typ "Antikörper" finden
Wirte Kaninchen (21), Ziege (5)
Reaktivitäten Human (19), Maus (8), Hund (2)
Applikationen Western Blot (WB) (21), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Enzyme Immunoassay (EIA) (2), ELISA (1), Immunfluoreszenz (IF) (1), Immunpräzipitation (IP) (1)
Konjugate Biotin (1), HRP (1)
Epitope N-Term (2)