Cyclin E (CCNE) Antikörper

Antigen: Cyclin E (CCNE)

Synonyme: Cyce, Ccne, CYCLE, cyce, fa18e07, wu:fa18e07, BG:DS07108.3, CDI7, CYCE, Cyc E, CyclE, CyeE, D-CycE, DmCycE, DmcyclinE, br37, cyclinE, dm-cycE, fond, l(2)05206, l(2)35Dd, l(2)br37, l(2)k02514, l(2)k02602, l(2)k05007, l35Dd, DmelCG3938, CG3938, NV18076

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunfluoreszenz (IF), Immunpräzipitation (IP), Kinaseaktivitätsassay (KAA), Western Blot (WB)

Produktnummer: ABIN285717

Produktbeschreibung

Weitere Bezeichnung: Cyclin E

Immunogen: Cyclin E antibody was raised in rabbit using a synthetic peptide derived from the c-terminus of human cyclin E as the immunogen.

Beschreibung: Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulationof cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Spezifität: Human, Rat, and Mouse. Others 1 mg/ml

Molekulargewicht: 50 kDa (predicted detection band MW)

Synonyme: Cyce, Ccne, CYCLE, cyce, fa18e07, wu:fa18e07, BG:DS07108.3, CDI7, CYCE, Cyc E, CyclE, CyeE, D-CycE, DmCycE, DmcyclinE, br37, cyclinE, dm-cycE, fond, l(2)05206, l(2)35Dd, l(2)br37, l(2)k02514, l(2)k02602, l(2)k05007, l35Dd, DmelCG3938, CG3938, NV18076

Anwendungen

Konzentration: ~1.0 mg/ml

Reinigung: Cyclin E antibody was purified by Protein A chromatography.

Buffer: Protein A purified IgG supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.

Lagerung: Store at 4 °C.

Forschungsgebiet: Krebs, Zellzyklus