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GSTZ1 Antikörper

KO Validated GSTZ1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856258
  • Target Alle GSTZ1 Antikörper anzeigen
    GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))
    Reaktivität
    • 25
    • 15
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    • 5
    Kaninchen
    Klonalität
    • 27
    • 3
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GSTZ1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 13
    • 13
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to GSTZ1 (glutathione transferase zeta 1)
    GSTZ1 antibody [N1C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human GSTZ1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product GSTZ1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: 293T

    Validation: KO/KD, Orthogonal, Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.98 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lei, Wang, Tang, Wang: "GSTZ1-1 downregulates Wnt/β-catenin signalling in hepatocellular carcinoma cells." in: FEBS open bio, Vol. 10, Issue 1, pp. 6-17, (2020) (PubMed).

    Li, Wang, Yang, Lei, Yang, Liang, Chen, Xia, Wang, Tang: "GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 438, (2020) (PubMed).

  • Target
    GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))
    Andere Bezeichnung
    glutathione S-transferase zeta 1 (GSTZ1 Produkte)
    Synonyme
    GSTZ1-1 antikoerper, MAAI antikoerper, MAI antikoerper, zgc:113898 antikoerper, zgc:92869 antikoerper, PSPTO3554 antikoerper, DDBDRAFT_0204466 antikoerper, DDBDRAFT_0231608 antikoerper, DDB_0204466 antikoerper, DDB_0231608 antikoerper, CG9362 antikoerper, Dmel\CG9362 antikoerper, gstz1 antikoerper, glutathione S-transferase zeta 1 antikoerper, glutathione transferase zeta 1 (maleylacetoacetate isomerase) antikoerper, maleylacetoacetate isomerase antikoerper, Glutathione S transferase Z1 antikoerper, glutathione S-transferase zeta 1 L homeolog antikoerper, GSTZ1 antikoerper, Gstz1 antikoerper, gstz1 antikoerper, maiA antikoerper, hmgC antikoerper, Patl_1448 antikoerper, Pnap_2807 antikoerper, Bind_0562 antikoerper, Bphyt_0577 antikoerper, Dtpsy_1678 antikoerper, Hbal_2638 antikoerper, mai antikoerper, BC1002_0299 antikoerper, Fbal_2576 antikoerper, Mesop_3937 antikoerper, GstZ1 antikoerper, gstz1.L antikoerper
    Hintergrund
    This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

    Cellular Localization: Cytoplasm
    Molekulargewicht
    24 kDa
    Gen-ID
    2954
    UniProt
    O43708
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