CYP46A1 Antikörper (Center)

Produktnummer ABIN2856057

Produktdetails anti-CYP46A1 Antikörper

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Bindungsspezifität: Center

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP46A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Human (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to CYP46A1 (cytochrome P450, family 46, subfamily A, polypeptide 1)
CYP46A1 antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CYP46A1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: Mouse brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CYP46A1

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Andere Bezeichnung: CYP46A1 (CYP46A1 Produkte)

Synonyme: CP46 antikoerper, CYP46 antikoerper, CYP46A1 antikoerper, zgc:109896 antikoerper, MGC147389 antikoerper, Cyp46 antikoerper, cytochrome P450 family 46 subfamily A member 1 antikoerper, cytochrome P450 family 46 subfamily A member 1 L homeolog antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 antikoerper, cytochrome P450, family 46 antikoerper, cytochrome P450 46A1 antikoerper, cytochrome P450, family 46, subfamily a, polypeptide 1 antikoerper, cholesterol 24-hydroxylase antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1 antikoerper, CYP46A1 antikoerper, cyp46a1.L antikoerper, cyp46a1.1 antikoerper, cyp46a1 antikoerper, PTRG_08343 antikoerper, PTRG_09667 antikoerper, Cyp46a1 antikoerper, Sgly_1093 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Cellular Localization: Endoplasmic reticulum membrane , Microsome membrane

Molekulargewicht: 57 kDa

Gen-ID: 10858