HPD Antikörper

Produktnummer ABIN2855744

Produktdetails anti-HPD Antikörper

Target: HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HPD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to HPD (4-hydroxyphenylpyruvate dioxygenase)
HPD antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human HPD. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-HPD Antikörper (ABIN2855744)

Shan, Lu, Li, Sheng, Fan, Qi, Liu, Zhang: "4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis." in: Cell death & disease, Vol. 10, Issue 7, pp. 525, (2020) (PubMed).

Details zu HPD

Target: HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

Andere Bezeichnung: 4-hydroxyphenylpyruvate dioxygenase (HPD Produkte)

Synonyme: fb58f02 antikoerper, hpd antikoerper, wu:fb58f02 antikoerper, zgc:56326 antikoerper, zgc:92456 antikoerper, MGC146689 antikoerper, BA0240 antikoerper, PSPTO3553 antikoerper, DDBDRAFT_0203373 antikoerper, DDBDRAFT_0231603 antikoerper, DDBDRAFT_0231604 antikoerper, DDB_0203373 antikoerper, DDB_0231603 antikoerper, DDB_0231604 antikoerper, hppd antikoerper, 4-HPPD antikoerper, 4HPPD antikoerper, GLOD3 antikoerper, HPPDASE antikoerper, PPD antikoerper, 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE antikoerper, F12K11.9 antikoerper, F12K11_9 antikoerper, HPD antikoerper, P-HYDROXYPHENYLPYRUVATE DIOXYGENASE antikoerper, phytoene desaturation 1 antikoerper, Fla antikoerper, Flp antikoerper, Hppd antikoerper, Laf antikoerper, 4-hydroxyphenylpyruvate dioxygenase a antikoerper, 4-hydroxyphenylpyruvate dioxygenase antikoerper, 4-hydroxyphenylpyruvate dioxygenase b antikoerper, 4-hydroxyphenylpyruvate dioxygenase L homeolog antikoerper, 4-hydroxyphenylpyruvic acid dioxygenase antikoerper, hpda antikoerper, HPD antikoerper, hpdb antikoerper, hpd.L antikoerper, hpd antikoerper, BA_0240 antikoerper, hppD antikoerper, Hpd antikoerper, PDS1 antikoerper

Hintergrund: The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 45 kDa

Gen-ID: 3242

UniProt: P32754