PPP2R1A Antikörper (Center)

Produktnummer ABIN2855322

Produktdetails anti-PPP2R1A Antikörper

Target: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Ratte (Rattus), Schwein, Rhesusaffen

Kreuzreaktivität (Details): Rat (100 %), Pig (100 %), Rhesus Monkey (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to PPP2R1A (serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform)
PPP2R1A antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PPP2R1A. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:1000-1:10000*

Kommentare:

Positive Control: HeLa , NIH-3T3 , JC , BCL-1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-PPP2R1A Antikörper (ABIN2855322)

Yen, Chien, Lai, Chen, Chuong, Hung, Hung: "PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." in: Cells, Vol. 9, Issue 1, (2020) (PubMed).

Details zu PPP2R1A

Target: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Andere Bezeichnung: PPP2R1A (PPP2R1A Produkte)

Synonyme: PP2A-Aalpha antikoerper, PP2AAALPHA antikoerper, PR65A antikoerper, PR65 antikoerper, pp2a-aalpha antikoerper, pp2aaalpha antikoerper, ppp2r1a antikoerper, pr65a antikoerper, wu:fa02h04 antikoerper, zgc:56296 antikoerper, 6330556D22Rik antikoerper, PP2A antikoerper, ppp2r1a-a antikoerper, ppp2r1a-b antikoerper, protein phosphatase 2 scaffold subunit Aalpha antikoerper, protein phosphatase 2 scaffold subunit A alpha antikoerper, protein phosphatase 2 regulatory subunit A, alpha L homeolog antikoerper, protein phosphatase 2 regulatory subunit A, alpha antikoerper, protein phosphatase 2, regulatory subunit A, beta a antikoerper, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform antikoerper, protein phosphatase 2, regulatory subunit A, alpha isoform antikoerper, protein phosphatase 2, regulatory subunit A, alpha antikoerper, protein phosphatase 2 regulatory subunit A, alpha S homeolog antikoerper, PPP2R1A antikoerper, Ppp2r1a antikoerper, ppp2r1a.L antikoerper, ppp2r1a antikoerper, ppp2r1ba antikoerper, LOC583227 antikoerper, ppp2r1a.S antikoerper

Hintergrund: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A.

Molekulargewicht: 65 kDa

Gen-ID: 5518

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, M Phase, Hepatitis C, Toll-Like Receptors Cascades