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Ensa Antikörper

KO Validated ENSA Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855066
  • Target Alle Ensa (ENSA) Antikörper anzeigen
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    Reaktivität
    • 45
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 2
    Kaninchen
    Klonalität
    • 43
    • 2
    Polyklonal
    Konjugat
    • 14
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ensa Antikörper ist unkonjugiert
    Applikation
    • 34
    • 21
    • 14
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to ENSA (endosulfine alpha)
    ENSA antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ENSA. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: 293T

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.6 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    Andere Bezeichnung
    endosulfine alpha (ENSA Produkte)
    Synonyme
    ARPP-19e antikoerper, 1700020C18Rik antikoerper, 2610007F17Rik antikoerper, AI451924 antikoerper, ensa antikoerper, si:dkeyp-24a7.3 antikoerper, ensaa antikoerper, endosulfine alpha antikoerper, endosulfine alpha a antikoerper, endosulfine alpha S homeolog antikoerper, ENSA antikoerper, Ensa antikoerper, ensa antikoerper, ensaa antikoerper, ensa.S antikoerper
    Hintergrund
    The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Cellular Localization: Cytoplasm
    Molekulargewicht
    13 kDa
    Gen-ID
    2029
    UniProt
    O43768
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