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POLG Antikörper (C-Term)

POLG Reaktivität: Human WB, IHC (p), IF, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854742
  • Target Alle POLG Antikörper anzeigen
    POLG (Polymerase (DNA Directed), gamma (POLG))
    Bindungsspezifität
    • 15
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 41
    • 21
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 2
    Kaninchen
    Klonalität
    • 39
    • 4
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLG Antikörper ist unkonjugiert
    Applikation
    • 38
    • 15
    • 13
    • 13
    • 11
    • 11
    • 7
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Kreuzreaktivität
    Human, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to DNA polymerase gamma (polymerase (DNA directed), gamma)
    DNA polymerase gamma antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human DNA polymerase gamma. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Rat testis , MCF-7 , MDA-MB-231

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.67 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    POLG (Polymerase (DNA Directed), gamma (POLG))
    Andere Bezeichnung
    DNA polymerase gamma (POLG Produkte)
    Synonyme
    POLG antikoerper, MDP1 antikoerper, MIRAS antikoerper, MTDPS4A antikoerper, MTDPS4B antikoerper, PEO antikoerper, POLG1 antikoerper, POLGA antikoerper, SANDO antikoerper, SCAE antikoerper, AA409516 antikoerper, PolgA antikoerper, polymerase (DNA) gamma, catalytic subunit L homeolog antikoerper, DNA polymerase gamma, catalytic subunit antikoerper, polymerase (DNA directed), gamma antikoerper, polg.L antikoerper, Polg antikoerper, POLG antikoerper, polg antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Mitochondrion
    Molekulargewicht
    140 kDa
    Gen-ID
    5428
    UniProt
    P54098
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