HRH4 Antikörper (N-Term)

Produktnummer ABIN2854739

Produktdetails anti-HRH4 Antikörper

Target: HRH4 (Histamine Receptor H4 (HRH4))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to Histamine H4 Receptor (histamine receptor H4)
Histamine H4 Receptor antibody [N1N2], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H4 Receptor. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Jurkat , Raji , NCI-H929 , human shHRH4-transfected HeLa cells

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-HRH4 Antikörper (ABIN2854739)

Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

Details zu HRH4

Target: HRH4 (Histamine Receptor H4 (HRH4))

Andere Bezeichnung: histamine receptor H4 (HRH4 Produkte)

Synonyme: AXOR35 antikoerper, BG26 antikoerper, GPCR105 antikoerper, GPRv53 antikoerper, H4 antikoerper, H4R antikoerper, HH4R antikoerper, HRH4 antikoerper, histamine receptor H4 antikoerper, HRH4 antikoerper, Hrh4 antikoerper

Hintergrund: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Molekulargewicht: 44 kDa

Gen-ID: 59340

UniProt: Q9H3N8