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ADAMTS5 Antikörper (C-Term)

ADAMTS5 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854716
  • Target Alle ADAMTS5 Antikörper anzeigen
    ADAMTS5 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 54
    • 27
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 52
    • 3
    • 2
    Kaninchen
    Klonalität
    • 54
    • 3
    Polyklonal
    Konjugat
    • 25
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADAMTS5 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 29
    • 9
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to ADAMTS5 (A disintegrin and metalloproteinase with thrombospondin motifs 5)
    ADAMTS5 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ADAMTS5. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ADAMTS5 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HCT116, MCF-7 , JC

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Wang, Ye, Ye, Wang, Liu, Jiang, Xu, Zhang, Chen, Wan: "ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease." in: Disease markers, Vol. 2019, pp. 6129748, (2020) (PubMed).

  • Target
    ADAMTS5 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))
    Andere Bezeichnung
    ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5 Produkte)
    Synonyme
    9530092O11Rik antikoerper, ADAM-TS5 antikoerper, ADAMTS1 antikoerper, ADAMTS11 antikoerper, AI481094 antikoerper, ASMP-2 antikoerper, ADAM-TS 11 antikoerper, ADAM-TS 5 antikoerper, ADAMTS-11 antikoerper, ADAMTS-5 antikoerper, ADMP-2 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 5 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 5 antikoerper, ADAMTS5 antikoerper, adamts5 antikoerper, Adamts5 antikoerper
    Hintergrund
    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

    Molekulargewicht
    102 kDa
    Gen-ID
    11096
    UniProt
    Q9UNA0
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