SCN1B Antikörper (N-Term)

Produktnummer ABIN2844301

Produktdetails anti-SCN1B Antikörper

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Bindungsspezifität: AA 63-90, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, Rb, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SCN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human SCN1B.

Klon: RB22198

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Details zu SCN1B

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Andere Bezeichnung: SCN1B (SCN1B Produkte)

Synonyme: GEFSP1 antikoerper, sodium channel, voltage-gated, type I, beta antikoerper, sodium voltage-gated channel beta subunit 1 antikoerper, Scn1b antikoerper, SCN1B antikoerper

Hintergrund: Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. SCN1B encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 24707

Gen-ID: 6324

NCBI Accession: NP_001028, NP_950238

UniProt: Q07699