Complement Component 5 (C5) (AA 253-281), (N-Term) Antikörper

Details zu Produkt Nr. ABIN2842347, Anbieter: Anmelden zum Anzeigen
Antigen
  • C5
  • LOC565774
  • C5a
  • C5b
  • CPAMD4
  • Hc
  • RGD1561905
  • He
  • complement component 5
  • similar to complement component C5-1
  • hemolytic complement
  • C5
  • LOC565774
  • Hc
Epitop
AA 253-281, N-Term
24
15
13
7
6
3
2
2
2
1
1
1
1
Reaktivität
Human
146
22
10
7
2
2
2
1
Wirt
Kaninchen
86
76
11
6
Klonalität (Klon)
Polyklonal ()
Konjugat
Unkonjugiert
14
12
6
6
5
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
105
82
28
22
19
16
13
10
10
9
9
7
6
5
4
3
2
2
2
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 AA from the N-terminal region of human C5.
Klon RB21866
Isotyp IgG
Spezifität This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260~289 amino acids from the N-terminal region of human C5.
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung C5 (C5 Antibody Abstract)
Hintergrund C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Synonyms: Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, CPAMD4, C5
Molekulargewicht 188305 DA
Gen-ID 727
UniProt P01031
Pathways Komplementsystem, Carbohydrate Homeostasis
Applikationshinweise WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.48 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Complement Component 5 (C5) (AA 253-281), (N-Term) antibody (ABIN2842347) Western blot analysis of C5 Antibody (N-term) (ABIN652518) in HL-60 cell line lysates...
Immunohistochemistry (IHC) image for anti-Complement Component 5 (C5) (AA 253-281), (N-Term) antibody (ABIN2842347) Formalin-fixed and paraffin-embedded human breast carcinoma with C5 Antibody (N-term)...
Flow Cytometry (FACS) image for anti-Complement Component 5 (C5) (AA 253-281), (N-Term) antibody (ABIN2842347) Flow cytometric analysis of MDA-231 cells using C5 Antibody (N-term)(bottom histogram...
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