Colony Stimulating Factor 1 Receptor (CSF1R) Antikörper

Antigen: Colony Stimulating Factor 1 Receptor (CSF1R)

Synonyme: MGC89146, FMS, CSFR, FIM2, C-FMS, CD115, Fms, Csfmr, Fim-2, CSF-1R, M-CSFR, AI323359

Klonalität: Monoklonal (AFS98)

Wirt: Ratte

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS), Funktionale Studien (Func)

Produktnummer: ABIN282311

Produktbeschreibung

Weitere Bezeichnung: CD115

Isotyp: IgG2a, kappa chain  (Passende Sekundärantikörper)

Klon: AFS98

Spezifität: The AFS98 monoclonal antibody reacts with the mouse CD115 molecule, a receptor for macrophage colony stimulating factor (M -CSF) or colony stimulating factor -1 (CSF -1). CD115 is expressed by monocyte, macrophage, osteoclast, and some epithelial cells. It is a 150 kDa c -fms gene product and belongs to immunoglobulin family. CSF -1 signaling through CSF -1R regulates the proliferation and differentiation of cells in the monocytic lineage., Mouse

Anwendungen

Applikationshinweise: The AFS98 antibody has been tested by blocking of fluorochrome conjugated AFS98 in flow cytometric analysis of peritoneal exudate cells. This can be used at less than or equal to 1 µg per million cells in a 100 µl total staining volume. It is recommended that the The AFS98 antibody has been reported for use in flow cytometric analysis. It has also been reported in blocking of ligand binding.

Buffer: Phosphate buffer pH 7.2,150 mM NaCl, No NaN3

Lagerung: Store at 4 °C.Avoid repeated freeze/thaw cycles.KEEP CONTENTS STERILE.Endotoxin Level: Less than 0.001 ng/ug antibody, as determined by the LAL assay.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Surface staining of thioglycolate induced PEC with anti-mouse CD115 (AFS98) PE. Appropriate isotype controls were used (open histogram). Cells in the large scatter population were used for analysis.