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HGD Antikörper (AA 351-445) (Alexa Fluor 594)

HGD Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2814318
  • Target Alle HGD Antikörper anzeigen
    HGD (Homogentisate 1,2-Dioxygenase (HGD))
    Bindungsspezifität
    • 14
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-445
    Reaktivität
    • 31
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 41
    • 5
    Kaninchen
    Klonalität
    • 43
    • 3
    Polyklonal
    Konjugat
    • 19
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HGD Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 35
    • 14
    • 12
    • 12
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HGD
    Isotyp
    IgG
    Top Product
    Discover our top product HGD Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HGD (Homogentisate 1,2-Dioxygenase (HGD))
    Andere Bezeichnung
    HGD (HGD Produkte)
    Synonyme
    CG4779 antikoerper, Dmel\\CG4779 antikoerper, PSPTO3551 antikoerper, DDBDRAFT_0185702 antikoerper, DDBDRAFT_0191461 antikoerper, DDB_0185702 antikoerper, DDB_0191461 antikoerper, Hgo antikoerper, aku antikoerper, hgo antikoerper, AKU antikoerper, HGO antikoerper, homogentisate 1,2-dioxygenase antikoerper, Homogentisate 1,2-dioxygenase antikoerper, homogentisate 1, 2-dioxygenase antikoerper, homogentisate 1,2-dioxygenase L homeolog antikoerper, hgo antikoerper, HGD antikoerper, hmgA antikoerper, Shewana3_2481 antikoerper, hgd antikoerper, BC1002_0545 antikoerper, BC1003_0502 antikoerper, BC1001_0489 antikoerper, Sinme_2995 antikoerper, Sphch_0441 antikoerper, Hgd antikoerper, hgd.L antikoerper
    Hintergrund

    Synonyms: 2-dioxygenase, AKU, FLJ94126, hgd, HGD_HUMAN, HGO, Homogentisate 1 2 dioxygenase, Homogentisate 1, Homogentisate oxidase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.

    Background: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyze the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterized by urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

    Gen-ID
    3081
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