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GDAP1 Antikörper (AA 151-230) (Alexa Fluor 594)

GDAP1 Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2813656
  • Target Alle GDAP1 Antikörper anzeigen
    GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
    Bindungsspezifität
    • 14
    • 2
    • 2
    • 1
    • 1
    AA 151-230
    Reaktivität
    • 26
    • 15
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 28
    • 1
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GDAP1 Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 22
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GDAP1
    Isotyp
    IgG
    Top Product
    Discover our top product GDAP1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
    Andere Bezeichnung
    GDAP1 (GDAP1 Produkte)
    Synonyme
    CMT4 antikoerper, CMT4A antikoerper, CMTRIA antikoerper, ganglioside induced differentiation associated protein 1 antikoerper, ganglioside-induced differentiation-associated-protein 1 antikoerper, GDAP1 antikoerper, Gdap1 antikoerper
    Hintergrund

    Synonyms: Ganglioside induced dferentiation associated protein 1, Ganglioside-induced dferentiation-associated protein 1, GDAP1, GDAP1_HUMAN.

    Background: Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.

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