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DIRC2 Antikörper (AA 51-150) (Alexa Fluor 594)

DIRC2 Reaktivität: Human, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2812393
  • Target Alle DIRC2 Antikörper anzeigen
    DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))
    Bindungsspezifität
    • 14
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 32
    • 15
    • 10
    • 2
    • 2
    • 2
    • 1
    Human, Ratte
    Wirt
    • 32
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DIRC2 Antikörper ist konjugiert mit Alexa Fluor 594
    Applikation
    • 25
    • 12
    • 12
    • 11
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Dog,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DIRC2
    Isotyp
    IgG
    Top Product
    Discover our top product DIRC2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))
    Andere Bezeichnung
    DIRC2 (DIRC2 Produkte)
    Synonyme
    MGC80843 antikoerper, zgc:92095 antikoerper, rcc4 antikoerper, MGC69320 antikoerper, RCC4 antikoerper, disrupted in renal carcinoma 2 antikoerper, disrupted in renal carcinoma 2 L homeolog antikoerper, disrupted in renal carcinoma 2 (human) antikoerper, DIRC2 antikoerper, dirc2.L antikoerper, dirc2 antikoerper, Dirc2 antikoerper
    Hintergrund

    Synonyms: Disrupted in renal carcinoma protein 2, DIRC 2, Disrupted in renal cancer protein 2, Disrupted in renal carcinoma 2, FLJ14784, NP_116228, RCC 4, RCC4, Renal cell carcinoma 4, DIRC2_HUMAN.

    Background: Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.

    Gen-ID
    84925
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