Colony Stimulating Factor 1 Receptor (CSF1R) Antikörper

Antigen: Colony Stimulating Factor 1 Receptor (CSF1R)

Synonyme: MGC89146, FMS, CSFR, FIM2, C-FMS, CD115, Fms, Csfmr, Fim-2, CSF-1R, M-CSFR, AI323359

Klonalität: Monoklonal (AFS98)

Wirt: Ratte

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS), Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN280601

Produktbeschreibung

Weitere Bezeichnung: CD115

Format: Affinity-purified

Isotyp: IgG2a, kappa chain  (Passende Sekundärantikörper)

Klon: AFS98

Spezifität: The AFS98 monoclonal antibody reacts with the mouse CD115 molecule, a receptor for macrophage colony stimulating factor (M -CSF) or colony stimulating factor -1 (CSF -1). CD115 is expressed by monocyte, macrophage, osteoclast, and some epithelial cells. It is a 150 kDa c -fms gene product and belongs to immunoglobulin family. CSF -1 signaling through CSF -1R regulates the proliferation and differentiation of cells in the monocytic lineage., Mouse

Anwendungen

Applikationshinweise: The AFS98 antibody has been tested by blocking of fluorochrome conjugated AFS98 in flow cytometric analysis of peritoneal exudate The AFS98 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistochemical staining of frozen tissue sections. It has also been reported in blocking of ligand binding. (Please use Functional Grade purified AFS98, cat. 16 -1152, in functional assays.)

Buffer: Phosphate buffer pH 7.2,150 mM NaCl, 0.09% NaN3

Lagerung: Store at 4 °C.Avoid repeated freeze/thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Staining of thioglycolate -induced PEC cells with 0.25 µg of Purified Rat IgG2a Iso Cntrl (ABIN287084) (open histogram) or 0.25 µg of Purified anti -mouse CD115 (AFS98) (colored histogram) followed by Biotin Anti -Rat IgG (ABIN286915)and SAv -PE (ABIN286891). Total viable cells were used for analysis.