MARCH3 Antikörper (Alexa Fluor 594)

Produktnummer ABIN2804008

Produktdetails anti-MARCH3 Antikörper (Alexa Fluor 594)

Target: MARCH3 (Membrane-Associated Ring Finger (C3HC4) 3, E3 Ubiquitin Protein Ligase (MARCH3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH3 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MARCH3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MARCH3

Target: MARCH3 (Membrane-Associated Ring Finger (C3HC4) 3, E3 Ubiquitin Protein Ligase (MARCH3))

Andere Bezeichnung: MARCH3 (MARCH3 Produkte)

Synonyme: 6330411I15Rik antikoerper, A530081L18Rik antikoerper, AI843639 antikoerper, MARCH-III antikoerper, RNF173 antikoerper, membrane-associated ring finger (C3HC4) 3 antikoerper, membrane associated ring-CH-type finger 3 antikoerper, March3 antikoerper, MARCH3 antikoerper

Hintergrund:

Synonyms: E3 ubiquitin-protein ligase MARCH3, FLJ20096, MARCH-III, March3, MARH3_HUMAN, Membrane associated ring finger C3HC4 3, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, RING finger protein 173, RNF173.

Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH3 (membrane-associated ring finger (C3HC4) 3), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger. Involved in the pathway of protein modification, MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events.

Gen-ID: 115123