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Caveolin-1 Antikörper

CAV1 Reaktivität: Human, Ratte, Maus WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1944910
  • Target Alle Caveolin-1 (CAV1) Antikörper anzeigen
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    Reaktivität
    • 113
    • 68
    • 54
    • 15
    • 11
    • 9
    • 9
    • 9
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 99
    • 17
    • 6
    • 2
    Kaninchen
    Klonalität
    • 94
    • 30
    Polyklonal
    Konjugat
    • 88
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Caveolin-1 Antikörper ist unkonjugiert
    Applikation
    • 98
    • 38
    • 32
    • 29
    • 27
    • 17
    • 16
    • 16
    • 16
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Isotyp
    IgG
    Top Product
    Discover our top product CAV1 Primärantikörper
  • Applikationshinweise
    IF: 1:100. WB: 1:1000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Lagerung
    4 °C,-20 °C
  • Vainonen, Aboulaich, Turkina, Strålfors, Vener: "N-terminal processing and modifications of caveolin-1 in caveolae from human adipocytes." in: Biochemical and biophysical research communications, Vol. 320, Issue 2, pp. 480-6, (2004) (PubMed).

    Engelman, Zhang, Lisanti: "Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines." in: FEBS letters, Vol. 448, Issue 2-3, pp. 221-30, (1999) (PubMed).

    Hurlstone, Reid, Reeves, Fraser, Strathdee, Rahilly, Parkinson, Black: "Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines." in: Oncogene, Vol. 18, Issue 10, pp. 1881-90, (1999) (PubMed).

    Glenney: "The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles." in: FEBS letters, Vol. 314, Issue 1, pp. 45-8, (1992) (PubMed).

  • Target
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    Andere Bezeichnung
    caveolin 1 (CAV1 Produkte)
    Synonyme
    fc07c04 antikoerper, wu:fc07c04 antikoerper, Cav-1 antikoerper, bscl3 antikoerper, cav1 antikoerper, cav1a antikoerper, cgl3 antikoerper, vip21 antikoerper, cav1b antikoerper, caveolin-1 antikoerper, cav antikoerper, mstp085 antikoerper, Caveolin-1 antikoerper, CAV1 antikoerper, cav-1 antikoerper, Cav antikoerper, caveolin 1 antikoerper, BSCL3 antikoerper, CGL3 antikoerper, MSTP085 antikoerper, PPH3 antikoerper, VIP21 antikoerper, caveolin 1 antikoerper, caveolin 1 L homeolog antikoerper, caveolin 1 S homeolog antikoerper, caveolin 1, caveolae protein antikoerper, caveolin 1, caveolae protein, 22kDa antikoerper, Caveolin antikoerper, cav1 antikoerper, cav1.L antikoerper, cav1.S antikoerper, CAV1 antikoerper, Cav1 antikoerper, cav-1 antikoerper
    Hintergrund
    May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
    Molekulargewicht
    20472 Da
    Gen-ID
    857
    UniProt
    Q03135
    Pathways
    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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