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ADRA2B Antikörper

ADRA2B Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1944814
  • Target Alle ADRA2B Antikörper anzeigen
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    Reaktivität
    • 22
    • 6
    • 4
    Human
    Wirt
    • 22
    • 3
    • 1
    Kaninchen
    Klonalität
    • 23
    • 3
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADRA2B Antikörper ist unkonjugiert
    Applikation
    • 17
    • 9
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Isotyp
    IgG1
    Top Product
    Discover our top product ADRA2B Primärantikörper
  • Applikationshinweise
    IF: 1:100. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Lagerung
    4 °C,-20 °C
  • Cayla, Heinonen, Viikari, Schaak, Snapir, Bouloumié, Karvonen, Pesonen, Scheinin, Paris: "Cloning, characterisation and identification of several polymorphisms in the promoter region of the human alpha2B-adrenergic receptor gene." in: Biochemical pharmacology, Vol. 67, Issue 3, pp. 469-78, (2004) (PubMed).

    Small, Brown, Forbes, Liggett: "Polymorphic deletion of three intracellular acidic residues of the alpha 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization." in: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 4917-22, (2001) (PubMed).

    Lomasney, Lorenz, Allen, King, Regan, Yang-Feng, Caron, Lefkowitz: "Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 13, pp. 5094-8, (1990) (PubMed).

    Weinshank, Zgombick, Macchi, Adham, Lichtblau, Branchek, Hartig: "Cloning, expression, and pharmacological characterization of a human alpha 2B-adrenergic receptor." in: Molecular pharmacology, Vol. 38, Issue 5, pp. 681-8, (1990) (PubMed).

  • Target
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    Andere Bezeichnung
    Adrenergic Receptor alpha-2B (ADRA2B Produkte)
    Synonyme
    ADRA2L1 antikoerper, ADRA2RL1 antikoerper, ADRARL1 antikoerper, ALPHA2BAR antikoerper, alpha-2BAR antikoerper, Adra-2b antikoerper, [a]2B antikoerper, alpha2-C2 antikoerper, alpha2B antikoerper, ADRA2B antikoerper, zgc:194747 antikoerper, Adra2b antikoerper, adrenoceptor alpha 2B antikoerper, adrenergic receptor, alpha 2b antikoerper, adrenergic, alpha-2B-, receptor antikoerper, adrenoceptor alpha 2C antikoerper, ADRA2B antikoerper, Adra2b antikoerper, ADRA2C antikoerper, adra2b antikoerper
    Hintergrund
    Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
    Molekulargewicht
    49954 Da
    Gen-ID
    151
    UniProt
    P18089
    Pathways
    EGFR Signaling Pathway, cAMP Metabolic Process
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