UBA2 Antikörper

Produktnummer ABIN1944808

Produktdetails anti-UBA2 Antikörper

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-UBA2 Antikörper (ABIN1944808)

Wiemann, Weil, Wellenreuther, Gassenhuber, Glassl, Ansorge, Böcher, Blöcker, Bauersachs, Blum, Lauber, Düsterhöft, Beyer, Köhrer, Strack, Mewes, Ottenwälder, Obermaier, Tampe, Heubner, Wambutt, Korn et al.: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." in: Genome research, Vol. 11, Issue 3, pp. 422-35, (2001) (PubMed).

Okuma, Honda, Ichikawa, Tsumagari, Yasuda: "In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2." in: Biochemical and biophysical research communications, Vol. 254, Issue 3, pp. 693-8, (1999) (PubMed).

Gong, Li, Millas, Yeh: "Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex." in: FEBS letters, Vol. 448, Issue 1, pp. 185-9, (1999) (PubMed).

Details zu UBA2

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Andere Bezeichnung: Uba2 (UBA2 Produkte)

Synonyme: ATSAE2 antikoerper, EMB2764 antikoerper, EMBRYO DEFECTIVE 2764 antikoerper, F3K23.23 antikoerper, F3K23_23 antikoerper, SUMO-ACTIVATING ENZYME 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ARX antikoerper, SAE2 antikoerper, AA986091 antikoerper, Arx antikoerper, Sae2 antikoerper, UBA1 antikoerper, Ubl1a2 antikoerper, Uble1b antikoerper, sae2 antikoerper, sae2-B antikoerper, uba2-a antikoerper, uba2-b antikoerper, uble1b-B antikoerper, sae2b antikoerper, uble1b antikoerper, wu:fi17g06 antikoerper, zgc:66354 antikoerper, SUMO1 activating enzyme subunit 2 antikoerper, SUMO-activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 antikoerper, ubiquitin-like modifier activating enzyme 2 antikoerper, ubiquitin like modifier activating enzyme 2 L homeolog antikoerper, MICPUN_63834 antikoerper, MICPUCDRAFT_36729 antikoerper, SAE2 antikoerper, UBA2 antikoerper, Uba2 antikoerper, uba2.L antikoerper, uba2 antikoerper

Hintergrund: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Molekulargewicht: 71224 Da

Gen-ID: 10054

UniProt: Q9UBT2