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TCEB1 Antikörper (N-Term)

TCEB1 Reaktivität: Human, Hund, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2792679
  • Target Alle TCEB1 Antikörper anzeigen
    TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 54
    • 15
    • 14
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Hund, Zebrafisch (Danio rerio)
    Wirt
    • 50
    • 3
    • 1
    Kaninchen
    Klonalität
    • 54
    Polyklonal
    Konjugat
    • 25
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCEB1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 26
    • 25
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    EHALTSGTIK AMLSGPGQFA ENETNEVNFR EIPSHVLSKV CMYFTYKVRY
    Kreuzreaktivität
    Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)
    Homologie
    Dog: 100%, Human: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TCEB1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TCEB1
    Top Product
    Discover our top product TCEB1 Primärantikörper
  • Applikationshinweise
    WB Suggested Anti-TCEB1 Antibody Titration: 0.2-1 µg/mL
    Positive Control: Raji cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 112 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
    Andere Bezeichnung
    TCEB1 (TCEB1 Produkte)
    Synonyme
    2610043E24Rik antikoerper, 2610301I15Rik antikoerper, AA407206 antikoerper, AI987979 antikoerper, AW049146 antikoerper, SIII antikoerper, eloC antikoerper, TCEB1 antikoerper, fb09f09 antikoerper, wu:fb09f09 antikoerper, zgc:111990 antikoerper, zgc:92635 antikoerper, elongin C antikoerper, elongin C L homeolog antikoerper, transcription elongation factor B (SIII), polypeptide 1b antikoerper, Eloc antikoerper, eloc.L antikoerper, ELOC antikoerper, tceb1b antikoerper
    Hintergrund
    TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    Alias Symbols: SIII, eloC
    Protein Interaction Partner: UBC, TCEB2, FUS, vif, METTL21C, SOCS4, CUL5, PRAME, POP1, MDM2, VHL, ASB18, ASB12, ASB14, ASB15, ASB9, ASB8, ASB7, ASB5, ASB10, ASB16, ASB13, ASB1, ASB3, APEX1, CUL2, Zswim8, ASB2, CPTP, CBX5, MRAS, JTB, RCAN2, SOCS1, CUL3, WNT7B, NEDD8, HIF1A, EFNB3, CYP
    Protein Size: 112
    Molekulargewicht
    12 kDa
    Gen-ID
    6921
    NCBI Accession
    NM_005648, NP_005639
    UniProt
    Q15369
    Pathways
    SARS-CoV-2 Protein Interaktom
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