C-JUN Antikörper (Jun Proto-Oncogene) (N-Term)

Details for Product anti-JUN Antibody No. ABIN2792650, Anbieter: Anmelden zum Anzeigen
Antigen
  • AP-1
  • AP1
  • c-Jun
  • fj36h07
  • wu:fj36h07
  • zgc:65863
  • B230310J22Rik
  • p39
  • BSK
  • BSK/DJNK
  • Bsk
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • JNK
  • JNK/SAPK
  • Jnk
  • Junk
  • SAPKa
  • dJNK
  • jnk
  • Junc
  • c-jun
  • CG2275
  • D-Jun
  • D-jun
  • D-jun/Jra
  • DJUN
  • DJun
  • Djun
  • Dmel\\CG2275
  • JRA
  • JUN
  • Jun
  • V
  • cJun
  • d-JRA
  • d-Jun
  • d-jun
  • dAP-1
  • dJRA
  • dJUN
  • dJra
  • dJun
  • djun
  • dm-Jun
  • jra
  • jun
  • l(2)46Ef
  • l(2)IA109
  • l(2R)IA109
  • Jun proto-oncogene, AP-1 transcription factor subunit
  • jun proto-oncogene S homeolog
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39)
  • basket
  • jun proto-oncogene
  • Jun-related antigen
  • jun proto-oncogene L homeolog
  • JUN
  • Jun
  • jun.S
  • jun
  • Cdk5r2
  • bsk
  • Jra
  • jun.L
Epitop
N-Term
89
74
51
46
45
43
43
30
30
20
19
18
17
15
15
15
15
10
8
8
7
7
6
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
880
536
481
69
58
48
43
42
37
32
23
20
13
8
8
5
4
3
2
2
2
1
1
Wirt
Kaninchen
767
129
4
2
1
Klonalität
Polyklonal
Konjugat
Dieser C-JUN Antikörper ist unkonjugiert
20
19
19
12
12
11
8
8
7
7
7
7
7
7
7
7
7
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
719
368
223
179
101
93
92
71
28
22
15
11
10
9
6
4
2
2
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human JUN
Sequenz TAKMETTFYD DALNASFLPS ESGPYGYSNP KILKQSMTLN LADPVGSLKP
Kreuzreaktivität Rind (Kuh), Hund, Human, Maus, Schwein, Ratte (Rattus)
Homologie Cow: 92%, Dog: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%, Sheep: 92%
Produktmerkmale This is a rabbit polyclonal antibody against JUN. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung AP-1 / c-Jun (JUN Antibody Abstract)
Hintergrund JUN gene is the putative transforming gene of avian sarcoma virus 17. I JUN is highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. JUN gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AP1, c-Jun, AP-1
Protein Interaction Partner: PPP3CA, SP1, HDAC1, GSK3B, FOS, ABL1, MAPK8, RFWD2, CORO7, EP300, STRN4, MAPRE3, CREB3, PRRC2A, MDM2, SMAD2, HSP90AA1, HSPA8, ATF2, APP, APLP2, GOPC, BBS7, ETS1, CREBBP, CASP9, UBC, NCOR1, EPAS1, DDIT3, BATF2, BATF3, BATF, FOSL1, SMARCD3, CEBPG, CEBPE, AT
Protein Size: 331
Molekulargewicht 36 kDa
Gen-ID 3725
NCBI Accession NM_002228, NP_002219
UniProt P05412
Pathways MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor
Applikationshinweise WB Suggested Anti-JUN Antibody Titration: 0.2-1 µg/mL
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 331 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Jun Proto-Oncogene (JUN) (N-Term) antibody (ABIN2792650) WB Suggested Anti-JUN Antibody Titration: 0.2-1 ug/ml
Positive Control: ...
Chromatin Immunoprecipitation (ChIP) image for anti-Jun Proto-Oncogene (JUN) (N-Term) antibody (ABIN2792650) Chromatin Immunoprecipitation (ChIP) Using JUN Antibody - N-terminal region (P100911_...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Jun Proto-Oncogene (JUN) (N-Term) antibody (ABIN2792650) Rabbit Anti-JUN Antibody ,Paraffin Embedded Tissue: Human alveolar cell
Cellul...
Produkt verwendet in: Russo, Pinsino, Costa, Bonaventura, Matranga, Zito: "The newly characterized Pl-jun is specifically expressed in skeletogenic cells of the Paracentrotus lividus sea urchin embryo." in: The FEBS journal, Vol. 281, Issue 17, pp. 3828-43, 2014 (PubMed).

Allgemeine Veröffentlichungen Adiseshaiah, Li, Vaz, Kalvakolanu, Reddy: "ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter." in: Biochemical and biophysical research communications, Vol. 371, Issue 2, pp. 304-8, 2008 (PubMed).

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