GATA1 Antikörper (N-Term)

Produktnummer ABIN2792607

Produktdetails anti-GATA1 Antikörper

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Schaf, Rind (Kuh), Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SGPEGLDAAA SSTAPSTATA AAAALAYYRD AEAYRHSPVF QVYPLLNCME

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GATA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GATA1

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-GATA1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 413 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GATA1 Antikörper (ABIN2792607)

de Vooght, van Wijk, van Solinge: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." in: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).

Details zu GATA1

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Andere Bezeichnung: GATA1 (GATA1 Produkte)

Synonyme: ERYF1 antikoerper, GATA-1 antikoerper, GF-1 antikoerper, GF1 antikoerper, NF-E1 antikoerper, NFE1 antikoerper, XLANP antikoerper, XLTDA antikoerper, XLTT antikoerper, Gata-1 antikoerper, Gf-1 antikoerper, eryf1 antikoerper, Eryf1 antikoerper, GATA1 antikoerper, gata-1 antikoerper, Gata1 antikoerper, si:dkeyp-77f7.5 antikoerper, gata1 antikoerper, gata1a-A antikoerper, xGATA-1 antikoerper, xgata1 antikoerper, XGATA-1B antikoerper, gata1b-A antikoerper, gta1 antikoerper, zg1 antikoerper, NF-E1a antikoerper, GATA binding protein 1 antikoerper, GATA binding protein 1 (globin transcription factor 1) antikoerper, amidase antikoerper, aspartyl/glutamyl-tRNA amidotransferase subunit A antikoerper, putative amidase antikoerper, GatA1 antikoerper, glutamyl-tRNA amidotransferase subunit A antikoerper, hematopietic transcription factor GATA-1 antikoerper, GATA binding protein 1b antikoerper, GATA binding protein 1 L homeolog antikoerper, GATA binding protein 1 S homeolog antikoerper, GATA binding protein 1a antikoerper, erythroid transcription factor antikoerper, GATA1 antikoerper, Gata1 antikoerper, gatA1 antikoerper, gata-1 antikoerper, gata1b antikoerper, gata1.L antikoerper, gata1.S antikoerper, gata1a antikoerper, LOC108348091 antikoerper

Hintergrund: GATA1 is a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERYF1, GF1, NFE1, GF-1, XLTT, GATA-1
Protein Interaction Partner: KRTAP10-5, CCDC24, HEXIM2, FBF1, KRTAP9-2, RADIL, FRS3, PRKAB2, HSPB1, HOXA1, AKT1, SPIB, SPI1, PRKAA1, HSPA4, FLI1, CASP3, SRA1, SUMO1, CEBPE, MAPK6, UBC, SKI, NME1, RAI1, ZBTB22, TRIM25, TAF7, TAX1BP3, ZZZ3, TRIM29, IKZF1, Rb1, ZFPM1, ZNF521, ZBTB16, HD
Protein Size: 413

Molekulargewicht: 43 kDa

Gen-ID: 2623

NCBI Accession: NM_002049, NP_002040

UniProt: P15976

Pathways: Cellular Response to Molecule of Bacterial Origin