APBA1 Antikörper (N-Term)

Produktnummer ABIN2792284

Produktdetails anti-APBA1 Antikörper

Target: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APBA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PPQQQHYVGR HQRGRALEDL RAQLGQEEEE RGECLARSAS TESGFHNHTD

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against APBA1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 837 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APBA1

Target: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Andere Bezeichnung: APBA1 (APBA1 Produkte)

Synonyme: APBA1 antikoerper, 6430513E09Rik antikoerper, Lin-10 antikoerper, Mint antikoerper, Mint1 antikoerper, Urop11 antikoerper, X11 antikoerper, X11alpha antikoerper, D9S411E antikoerper, LIN10 antikoerper, MINT1 antikoerper, X11A antikoerper, X11ALPHA antikoerper, amyloid beta precursor protein binding family A member 1 antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1b antikoerper, ketopantoate reductase antikoerper, 2-dehydropantoate 2-reductase antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 1 antikoerper, amyloid beta (A4) precursor protein binding, family A, member 1 antikoerper, APBA1 antikoerper, apba1b antikoerper, apbA1 antikoerper, apba1 antikoerper, Apba1 antikoerper

Hintergrund: APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Alias Symbols: D9S411E, MINT1, X11, X11A, X11ALPHA, LIN10
Protein Interaction Partner: STXBP1, CNTNAP4, NRXN1, CNTNAP3, KIF17, LIN7B, KCNJ12, CCS, CACNA1B, HTR2C, CASK, NOTCH1, STX1A, APP, PSEN1, LIN7A, PSEN2, LIN7C, DLG1, APBB1,
Protein Size: 837

Molekulargewicht: 93 kDa

Gen-ID: 320

NCBI Accession: NM_001163

UniProt: Q02410

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport